Table 2

Infection of pregnant mice with B. abortus virB4 mutant or vaccine strain S19 on day 4.5 of gestation.



Fetus
Placenta
Spleen





Strain
Mouse No.
Alive
Aborted
Alive
Aborted












No.
Weight (g)*
Bacterial No. (log)*
No.
Weight (g)*
Bacterial No. (log)*
Weight (g)*
Bacterial No. (log)*
Weight (g)*
Bacterial No. (log)*
Weight (g)
Bacterial No. (log)

virB4 mutant
1
15
1.51 (±0.21)
3.25 (±0.16)
0
-
-
0.11 (±0.01)
7.51 (±0.26)
-
-
0.16
5.41

2
16
1.43 (±0.18)
3.24 (±0.15)
0
-
-
0.14 (±0.01)
5.15 (±0.27)
-
-
0.20
5.38

3
16
1.62 (±0.13)
1.14 (±0.08)
0
-
-
0.12 (±0.02)
5.52 (±0.34)
-
-
0.15
4.80

4
13
1.51 (±0.15)
2.52 (±0.12)
0
-
-
0.12 (±0.02)
7.25 (±0.36)
-
-
0.21
5.61

5
14
1.72 (±0.17)
3.64 (±0.24)
0
-
-
0.14 (±0.01)
7.48 (±0.33)
-
-
0.18
5.41

S19
1
14
1.43 (±0.14))
2.54 (±0.24)
0
-
-
0.13 (±0.01)
7.52 (±0.27)
-
-
0.50
7.12

2
14
1.45 (±0.18)
2.24 (±0.20)
0
-
-
0.10 (±0.01)
7.51 (±0.35)
-
-
0.20
6.56

3
15
1.35 (±0.14)
3.23 (±0.16)
0
-
-
0.10 (±0.02)
7.58 (±0.41)
-
-
0.21
6.63

4
12
1.34 (±0.17)
3.17 (±0.27)
1
1.28
3.23
0.11 (±0.01)
7.64 (±0.21)
0.10
7.39
0.26
6.53

5
14
1.35 (±0.12)
3.26 (±0.12)
0
-
-
0.10 (±0.01)
7.62 (±0.29)
-
-
0.24
6.96

*Average number of fetuses or placentas.

Kim et al. BMC Microbiology 2005 5:22   doi:10.1186/1471-2180-5-22