|
Infection of pregnant mice with B. abortus virB4 mutant or vaccine strain S19 on day 4.5 of gestation. |
|||||||||||||
| Fetus |
Placenta |
Spleen |
|||||||||||
|
|
|
|
|||||||||||
| Strain |
Mouse No. |
Alive |
Aborted |
Alive |
Aborted |
||||||||
|
|
|
|
|
||||||||||
| No. |
Weight (g)* |
Bacterial No. (log)* |
No. |
Weight (g)* |
Bacterial No. (log)* |
Weight (g)* |
Bacterial No. (log)* |
Weight (g)* |
Bacterial No. (log)* |
Weight (g) |
Bacterial No. (log) |
||
|
|
|||||||||||||
| virB4 mutant |
1 |
15 |
1.51 (±0.21) |
3.25 (±0.16) |
0 |
- |
- |
0.11 (±0.01) |
7.51 (±0.26) |
- |
- |
0.16 |
5.41 |
| 2 |
16 |
1.43 (±0.18) |
3.24 (±0.15) |
0 |
- |
- |
0.14 (±0.01) |
5.15 (±0.27) |
- |
- |
0.20 |
5.38 |
|
| 3 |
16 |
1.62 (±0.13) |
1.14 (±0.08) |
0 |
- |
- |
0.12 (±0.02) |
5.52 (±0.34) |
- |
- |
0.15 |
4.80 |
|
| 4 |
13 |
1.51 (±0.15) |
2.52 (±0.12) |
0 |
- |
- |
0.12 (±0.02) |
7.25 (±0.36) |
- |
- |
0.21 |
5.61 |
|
| 5 |
14 |
1.72 (±0.17) |
3.64 (±0.24) |
0 |
- |
- |
0.14 (±0.01) |
7.48 (±0.33) |
- |
- |
0.18 |
5.41 |
|
|
|
|||||||||||||
| S19 |
1 |
14 |
1.43 (±0.14)) |
2.54 (±0.24) |
0 |
- |
- |
0.13 (±0.01) |
7.52 (±0.27) |
- |
- |
0.50 |
7.12 |
| 2 |
14 |
1.45 (±0.18) |
2.24 (±0.20) |
0 |
- |
- |
0.10 (±0.01) |
7.51 (±0.35) |
- |
- |
0.20 |
6.56 |
|
| 3 |
15 |
1.35 (±0.14) |
3.23 (±0.16) |
0 |
- |
- |
0.10 (±0.02) |
7.58 (±0.41) |
- |
- |
0.21 |
6.63 |
|
| 4 |
12 |
1.34 (±0.17) |
3.17 (±0.27) |
1 |
1.28 |
3.23 |
0.11 (±0.01) |
7.64 (±0.21) |
0.10 |
7.39 |
0.26 |
6.53 |
|
| 5 |
14 |
1.35 (±0.12) |
3.26 (±0.12) |
0 |
- |
- |
0.10 (±0.01) |
7.62 (±0.29) |
- |
- |
0.24 |
6.96 |
|
|
*Average number of fetuses or placentas. | |||||||||||||
Kim et al. BMC Microbiology 2005 5:22 doi:10.1186/1471-2180-5-22 |
|||||||||||||