Dynamics of success and failure in phage and antibiotic therapy in experimental infections

J J Bull¹ , Bruce R Levin² , Terry DeRouin² , Nina Walker² and Craig A Bloch³

¹Section of Integrative Biology and Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712-1023, USA

²Department of Biology, Emory University, Atlanta, GA 30322, USA

³Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI 48104, USA

author email corresponding author email

BMC Microbiology 2002, 2:35doi:10.1186/1471-2180-2-35


Published:	26 November 2002

Additional files

Additional File 1:

Sensitivity of Phage Replication Assay to Growth Conditions. This file explains some assumptions that underlie the Phage Replication Assay (PRA), how assay conditions may violate those assumptions and affect those values estimated, and how to minimize the effect of violating those assumptions. A mathematical model using differential equations is provided to evaluate the magnitudes of some of these effects.

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