Research article
Dynamics of success and failure in phage and antibiotic therapy in experimental infections
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* Corresponding author: Bruce R Levin blevin@emory.edu
1 Section of Integrative Biology and Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712-1023, USA
2 Department of Biology, Emory University, Atlanta, GA 30322, USA
3 Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI 48104, USA
BMC Microbiology 2002, 2:35 doi:10.1186/1471-2180-2-35
Published: 26 November 2002Additional files
Additional File 1:
Sensitivity of Phage Replication Assay to Growth Conditions. This file explains some assumptions that underlie the Phage Replication Assay (PRA), how assay conditions may violate those assumptions and affect those values estimated, and how to minimize the effect of violating those assumptions. A mathematical model using differential equations is provided to evaluate the magnitudes of some of these effects.
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