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Open Access Highly Accessed Research article

Diffusible signal factor (DSF) quorum sensing signal and structurally related molecules enhance the antimicrobial efficacy of antibiotics against some bacterial pathogens

Yinyue Deng12, Amy Lim1, Jasmine Lee1, Shaohua Chen2, Shuwen An1, Yi-Hu Dong1 and Lian-Hui Zhang12*

Author Affiliations

1 Institute of Molecular and Cell Biology, Proteos, 61 Biopolis Drive, Singapore 138673, Singapore

2 Guangdong Province Key Laboratory of Microbial Signals and Disease Control, College of Natural Resources and Environment, South China Agricultural University, Guangzhou, People’s Republic of China

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BMC Microbiology 2014, 14:51  doi:10.1186/1471-2180-14-51

Published: 27 February 2014

Additional files

Additional file 1: Figure S1:

Real-time PCR analysis of DSF effect on transcriptional expression of selected genes in B. cereus 10987. Table S1. The genes with increased or decreased expression in B. cereus 10987 after treatment with 50 μM DSF. Figure S2. The bacterial growth rate in the presence and absence of 50 μM DSF or its analogue. Figure S3. Effect of DSF signal and rhamnolipid on the growth rate of B. thuringiensis. Table S2. Bacterial strains used in this study.

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