Table 1

Deduced functions of ORFs in the biosynthetic gene cluster of PLYA
Gene Sizea Accession no. Proposed function Homologous protein species Identity/Similarity
orf03399 384 YP_003099796 Nucleotidyl transferase Actinosynnema mirum DSM 43827 64/73
orf03396 309 YP_004903951 putative sugar kinase Kitasatospora setae KM-6054 50/62
orf1 422 YP_003099794 3-dehydroquinate synthase Actinosynnema mirum DSM 43827 56/69
orf2 128 EID72461 MarR family transcriptional regulator Rhodococcus imtechensis RKJ300 71/83
orf3 146 ZP_09957194 Hypothetical protein Streptomyces chartreusis NRRL 12338 75/84
orf4 566 CAJ61212 Putative polyketide oxygenase/hydroxylase Frankia alni ACN14a 77/83
orf5 377 ZP_04706918 Alcohol dehydrogenase BadC Streptomyces roseosporus NRRL 11379 76/86
orf6 312 ZP_06582592 3-oxoacyl-[acyl-carrier-protein] synthase III Streptomyces roseosporus NRRL 15998 71/82
orf7 82 ZP_04706920 Hypothetical protein Streptomyces roseosporus NRRL 11379 59/75
orf8 82 ZP_04706921 Dihydrolipoamide succinyltransferase Streptomyces roseosporus NRRL 11379 65/81
orf9 326 ZP_06582595 2-oxoisovalerate dehydrogenase Streptomyces roseosporus NRRL 15998 75/87
orf10 303 ZP_04706923 Pyruvate dehydrogenase Streptomyces roseosporus NRRL 11379 74/84
plyA 71 YP_640626 MbtH-like protein Mycobacterium sp. MCS 80/87
plyB 225 YP_712760 Putative regulator Frankia alni ACN14a 76/84
plyC 528 YP_712761 A Frankia alni ACN14a 77/85
plyD 77 YP_712762 PCP Frankia alni ACN14a 85/94
plyE 395 YP_712763 Putative hydroxylase Frankia alni ACN14a 76/86
plyF 2583 ABV56588 C-A-PCP-E-C-A-PCP Kutzneria sp. 744 56/68
plyG 2809 ZP_05519638 C-A-PCP-E-C-A-PCP Streptomyces hygroscopicus ATCC 53653 73/82
plyH 1662 BAH04161 C-A-M-PCP-TE Streptomyces triostinicus 72/82
plyI 247 YP_712767 TE Frankia alni ACN14a 80/87
plyJ 312 YP_003112824 Daunorubicin resistance ABC transporter Catenulispora acidiphila DSM 44928 78/90
plyK 253 YP_712769 ABC transporter system Frankia alni ACN14a 71/81
plyL 1043 YP_003112826 Transcriptional regulator Catenulispora acidiphila DSM 44928 72/80
plyM 412 AAT45271 Cytochrome P450 monooxygenase Streptomyces tubercidicus 43/59
plyN 450 ZP_04604097 Aminotransferase class I and II Micromonospora sp. ATCC 39149 58/70
plyO 308 ZP_03862696 Polyketide fumonisin Kribbella flavida DSM 17836 48/64
plyP 270 ZP_04292518 L-proline 3-hydroxylase type II Bacillus cereus R309803 32/51
plyQ 88 YP_712776 PCP Frankia alni ACN14a 76/89
plyR 415 YP_712777 Cytochrome P450 monooxygenase Frankia alni ACN14a 77/85
plyS 245 AAT45287 TE Streptomyces tubercidicus 70/81
plyT 1031 YP_712779 KS-AT-ACP Frankia alni ACN14a 71/80
plyU 1872 YP_712780 KS-AT-DH-KR-ACP Frankia alni ACN14a 69/79
plyV 2199 YP_712781 KS-AT-DH-ER-KR-ACP Frankia alni ACN14a 70/78
plyW 1041 YP_712782 KS-AT-ACP Frankia alni ACN14a 72/82
plyX 1080 YP_712783 C-A-PCP Frankia alni ACN14a 62/72
plyY 253 ZP_04472110 TE Streptosporangium roseum DSM 43021 70/78
plyZ 79 YP_001612061 LysR family transcriptional regulator Sorangium cellulosum 65/77
orf11 287 YP_702564 Hypothetical protein Rhodococcus jostii RHA1 56/73
orf14742 170 YP_002777514 Hypothetical protein ROP_03220 Rhodococcus opacus B4 51/63

aNumbers are in amino acids.

Du et al.

Du et al. BMC Microbiology 2014 14:30   doi:10.1186/1471-2180-14-30

Open Data