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Open Access Research article

Identification and characterization of the biosynthetic gene cluster of polyoxypeptin A, a potent apoptosis inducer

Yanhua Du1, Yemin Wang1, Tingting Huang2, Meifeng Tao1, Zixin Deng1 and Shuangjun Lin1*

Author Affiliations

1 State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China

2 Current address: Department of Chemistry at the Scripps Research Institute, Jupiter, FL 33458, USA

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BMC Microbiology 2014, 14:30  doi:10.1186/1471-2180-14-30

Published: 8 February 2014

Additional files

Additional file 1:

Electronic supplementary materials are available: bacterial strains (Table S1), plasmids (Table S2), primers (Table S3), and the substrate-specific codon sequences (Table S4); sequence alignment (Figures S1-6) and mutant construction (Schemes S1-8).

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