Antioxidant can inhibit PCN-induced IL-8 release. Different concentrations of N-acetyl cysteine (NAC) (5, 10 or 20 mM) were added into fresh medium of PMA-differentiated U937 cells for 60 min before PCN was added. After 24 h, supernatants were collected and IL-8 concentrations were detected by ELISA. *p <0.05, **p < 0.01 compared with the PCN groups. PMA: phorbol 12-myristate 13-acetate.
Chai et al. BMC Microbiology 2014 14:26 doi:10.1186/1471-2180-14-26