Table 1

Occurrence of virulence factors in E. coli pathotypes
Virulence factors Pathotype
Non-pathogenic E. coli* Diarrhea-associated E. coli** ExPEC***
n = 399 (%) n = 179 (%) n = 603 (%)
Aggregative adherence plasmid pCVD432 - 13 (7.3) -
Invasive associated locus ial - 44 (24.6) -
Heat-stable enterotoxin st - 8 (4.5) -
Heat-labile enterotoxin lt - 7 (3.9) -
Intimin eaeA - 26 (14.5) -
Bundle-forming fimbriae bfpA - 1 (0.6) -
Invasion plasmid H ipaH - 19 (10.6) -
Aerobactin synthesis aer - 68 (38.0) 342 (56.7)
Fimbriae type 1 fimA 336 (84.2) 149 (83.2) 553 (91.7)
α-hemolysin α-hly - 3 (1.7) 88 (14.6)
Afimbrial adhesin afaI - 78 (43.6) -
Aerobactin synthesis iucC - 80 (44.7) 396 (65.7)
Cytotoxic necrotizing factor cnf1 - 1 (0.6) 43 (7.1)
S-fimbriae sfa - 6 (3.4) 227 (37.6)
P-fimbriae pap - 19 (10.6) 201 (33.3)
Shiga-toxin 1 stx1 - - -
Shiga-toxin 2 stx2 - - -
Enterohemolysin ehly - 9 (5.0) -

*E. coli strains with no detected genes for virulence factors or those possessing only gene for fimbriae type I (fimA gene).

**EAggEC - pCVD432 (aggregative adherence plasmid); ETEC - lt/st (heat-labile and heat-stable enterotoxin); EIEC - ial/ipaH (invasion associated locus/invasion plasmid H); EPEC – bfpA/eaeA (bundle-forming fimbriae/intimin); EHEC (stx1/stx2/ehly); DAEC – afaI (afimbrial adhesin I).

***E. coli strains which contain different virulence factors (except those that are typical for previously described diarrhea-associated E. coli) typical for extraintestinal E. coli strains (α-hemolysin, P-fimbriae, S-fimbriae, cytotoxic necrosis factor, aerobactin synthesis).

Micenková et al.

Micenková et al. BMC Microbiology 2014 14:109   doi:10.1186/1471-2180-14-109

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