Table 3

Codon usage bias in dengue virus
DENV-1 RSCU > 1 in Asian DENV RSCU < 1 in Asian DENV p value
RSCU > 1 in American DENV 91 160 0.02
RSCU <1 in American DENV 193 112
DENV-2 RSCU > 1 in Asian DENV RSCU < 1 in Asian DENV
RSCU > 1 in American DENV 35 121 0.000004
RSCU <1 in American DENV 155 79
DENV-3 RSCU > 1 in Asian DENV RSCU < 1 in Asian DENV
RSCU > 1 in American DENV 80 132 0.08
RSCU <1 in American DENV 138 116
DENV-4 RSCU > 1 in Central American DENV RSCU <1 in South American DENV
RSCU > 1 in Central American DENV 5 13 0.004

RSCU <1 in South

American DENV

22 16

Number of synonymous codons that are used either more than expected (frequent) or less than expected (rare) between Asian and American isolates of DENV serotype 1, 2 and 3 (or between South and Central American isolates of DENV4).

Behura and Severson

Behura and Severson BMC Microbiology 2013 13:37   doi:10.1186/1471-2180-13-37

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