Kinetics of antibody titer development in mice following immunization. Mice were immunized twice with 100 μl preparation containing 5 μg of different proteins on week 0 and 3, respectively, and were bled before immunization and at week 2, 5, 8 weeks after immunization for serological tests. BSA-VP4N20 was used to coat EIA plates to detect VP4N20-specific antibodies. Each bar represents the mean reciprocal log10 endpoint titers and standard error.
Zhao et al. BMC Microbiology 2013 13:287 doi:10.1186/1471-2180-13-287