Table 2

Rates of mutation and unequal sister chromatid recombination in wild-type and mutant haploid strains
Genotype Mutation rate (10-7) USCR rate (10-6)
Wild-type 4.0 (3.8, 7.4) [1] 1.0 (0.8, 1.2) [1]
rad51::LEU2 n.d. 1.4 (1.0, 1.8) [+1.4]
rad59::LEU2 7.5 (6.6, 8.6) [+1.9] 0.82 (0.43, 1.4) [-1.3]
rad59-Y92A 4.4 (3.9, 5.3) [+1.1] 1.3 (1.1, 1.8) [+1.3]
rad59-K174A 3.2 (1.8, 5.5) [-1.3] 1.1 (0.85, 2.1) [+1.1]
rad59-F180A 4.8 (4, 6.9) [+1.2] 0.61 (0.47, 0.95) [-1.6]
rad27::LEU2 200 (90, 590) [+50] 47 (39, 100) [+47]
rad27::LEU2 rad59-Y92A 220 (60, 510) [+55] 39 (25, 99) [+39]
rad27::LEU2 rad59-K174A 130 (110, 190) [+32.5] 38 (33, 53) [+38]
rad27::LEU2 rad59-F180A 190 (110, 500) [+47.5] 60 (49, 120) [+60]

Rates of CAN1 mutation or USCR were determined from at least 10 independent cultures as described in the Methods. The 95% confidence intervals are in parentheses. Fold decreases (−) and increases (+) from wild-type are in brackets. n.d. – not determined.

Liddell et al.

Liddell et al. BMC Microbiology 2013 13:229   doi:10.1186/1471-2180-13-229

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