|IL-1β secretion from F. tularensis-infected BMDM cells|
|Strain||IL-1β secretion (pg/ml)a|
|5 h||24 h|
|LVS||76.3 ± 10.9||497.1 ± 79.0|
|ΔpdpC||64.5 ± 27.2||112.1 ± 41.0*|
|ΔpdpC/pdpC||163.2 ± 50.2||506.9 ± 94.3|
aF. tularensis-infected, or uninfected (-) BMDM cells were incubated for 5 or 24 h. The average IL-1β secretion in pg/ml with standard errors of triplicate biological samples from one representative experiment, out of three, is shown. A Student’s t-test was used to determine if the IL-1β secretion was significantly different between LVS infected and mutant infected cells (*: P < 0.05, **: P < 0.01, ***: P < 0.001). BDL means that the concentration was below the detection limit of the assay (< 31.25 pg/ml).
b Only one of the triplicates was above BDL.
Lindgren et al.
Lindgren et al. BMC Microbiology 2013 13:20 doi:10.1186/1471-2180-13-20