This article is part of the supplement: Arthropod symbioses: from fundamental studies to pest and disease management
Research
Metabolic stasis in an ancient symbiosis: genome-scale metabolic networks from two Blattabacterium cuenoti strains, primary endosymbionts of cockroaches
1 Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, P.O. Box 22085, E-46071, València, Spain
2 Faculty of Pharmacy, University of Granada. Campus of Cartuja, E-18071. Granada, Spain
3 Departament de Genètica, Universitat de València, Spain
4 Departament de Bioquímica i Biologia Molecular, Universitat de València, Spain
5 Centre for Public Health Research (CSISP), E-46020. València, Spain
BMC Microbiology 2012, 12(Suppl 1):S5 doi:10.1186/1471-2180-12-S1-S5
Published: 18 January 2012Additional files
Additional file 1:
Description of the metabolic model of the Bge strain of B. cuenoti (host Blattella germanica), containing: a list of the GPR associations; a list of the reactions that were supposed to be placed although without any associated gene; a list of the exchange fluxes used in simulations and their constraints; a list of definitions of the metabolite abbreviations; and a list of the dead-end metabolites in the metabolic network.
Format: XLS Size: 216KB Download file
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Additional file 2:
Description of the metabolic model of the Pam strain of B. cuenoti (host Periplaneta americana), containing: the same kind of information as Additional file 1.
Format: XLS Size: 232KB Download file
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Additional file 3:
Differences in the cysteine biosynthesis pathway between the strains Bge and Pam. Sulfate constitutes the sulfur donor in the strain Bge, whereas this function is performed by hydrogen sulfide in the strain Pam. In green, genes exclusively present in B. cuenoti (strain Bge); in blue, genes extant in both bacterial strains, Bge and Pam. For all the compounds shown, see the list of abbreviations in the corresponding Metabolites section of Additional files 1 and 2.
Format: PPT Size: 105KB Download file
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Additional file 4:
Further details on the reconstruction of the networks
Format: DOCX Size: 17KB Download file
Additional file 5:
Metabolic network model of Bge strain in Systems Biology Markup Language (sbml) format [44], ready to perform simulations with COBRA toolbox [43].
Format: XML Size: 728KB Download file
Additional file 6:
Metabolic network model of Pam strain in Systems Biology Markup Language (sbml) format [44], ready to perform simulations with COBRA toolbox [43].
Format: XML Size: 693KB Download file
