Figure 2.

RDA-visualization of PCR-DGGE profile similarities. RDA visualization of microbiota profile similarities and ABO blood group types, revealing a clustering of the samples. Each dot represents a single individual and diamonds mark the calculated data centre points of the corresponding blood groups. P-value marks the statistical significance of the difference between blood group centres, computed with ANOVA-like permutation test from PCR-DGGE intensities grouped by ABO blood group (A) or by the presence of B-antigen (B). Dot colours for the ABO blood groups are as follows: A = red, B = blue, AB = green and O = black and for the B-antigen = blue and non-B antigen red, respectively. UNIV represent the PCR-DGGE obtained with the universal eubacterial primers (dominant bacteria), EREC with the Eubacterium rectaleClostridium coccoides primers and CLEPT with the Clostridium leptum primers. The RDA analysis shows clustering of samples according to ABO blood groups, especially according to the presence of the B antigen in the dominant and EREC group microbiota.

Mäkivuokko et al. BMC Microbiology 2012 12:94   doi:10.1186/1471-2180-12-94
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