Biofilm formation of S. aureus in vivo. Biofilm formation was assessed using a murine catheter-associated model of WT (NCTC8325) and ΔluxS (NCTC8325ΔluxS). Overnight culture of 5 × 107 CFU was injected into the catheters, which were implanted subcutaneously in the dorsal area of the mice. Results shown are the number of bacteria counted from the catheters after incubation for 3 days. Each point stands for one independent mouse. P value refers to a comparison between WT and ΔluxS and means statistically significant differences (P = 0.001) by Student's t test.
Yu et al. BMC Microbiology 2012 12:288 doi:10.1186/1471-2180-12-288