Open Access Research article

Characterization and ligand identification of a membrane progesterone receptor in fungi: existence of a novel PAQR in Sporothrix schenckii

Waleska Gonzalez-Velazquez1, Ricardo Gonzalez-Mendez2 and Nuri Rodriguez-del Valle1*

Author Affiliations

1 Department of Microbiology and Medical Zoology, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, San Juan PR 00936-5067, USA

2 Department of Radiological Sciences, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, San Juan, PR 00936-5067, USA

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BMC Microbiology 2012, 12:194  doi:10.1186/1471-2180-12-194

Published: 7 September 2012

Additional files

Additional file 1:

Amino acid sequence alignments of SsPAQR1 to other fungal protein homologues. The predicted amino acid sequence of S. schenckii SsPAQR1 and other fungal homologues proteins were aligned using MCoffee. In the alignment, black shading with white letters indicates 100% identity, gray shading with white letters indicates 75-99% identity; gray shading with black letters indicates 50-74% identity. Blue lines indicate the transmembrane domains of the SsPAQR1.

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Additional file 2:

TMHMM analysis of SsPAQR1 fungal protein homologues. The TMHMM analysis was done using sequences retrieved from GenBank by means of BLAST. Sequences A to J correspond to: A. capsulatus, A. nidulans, C. globosum, F. oxysporum, G. zeae, M. oryzae, N. crassa, P. anserina, P. brasiliensis and S. cerevisiae (Izh3), respectively.

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