Table 3

Classification of ArcA regulated genes according to Clusters of Orthologous Groups (COGs)

Functional Gene Groupsa

# of Genesb


ArcA-activated

ArcA-repressed


Cell division and chromosome partitioning

0

0


Cell envelope and biogenesis, outer membrane

4

4


Cell motility and secretion

1

12


Posttranslational modification, protein turnover, chaperones

1

3


Inorganic ion transport and metabolism

1

12


Signal transduction mechanisms

5

3


Cellular processesc

12

34


Defense Mechanismsc

1

1


Translation, ribosomal structure, and biogenesis

0

7


Transcription

8

18


DNA replication, recombination, and repair

2

4


Information storage and processingc

10

29


Intracell traffickingc

0

1


Energy production and conversion

9

18


Amino acid transport and metabolism

25

30


Nucleotide transport and metabolism

7

2


Carbohydrate transport and metabolism

20

16


Coenzyme metabolism

0

2


Lipid metabolism

1

7


Secondary metabolites biosynthesis, transport, and catabolism

12

4


Metabolismc

74

79


General function prediction only

8

21


Function unknown

8

24


Poorly characterized

23

67


Unknownc

39

112


Total

147

245


aThe differentially expressed genes were classified according to clusters of orthologous groups (COGs) as defined at http://www.ncbi.nlm.nih.gov/COG webcite.

bNumber of genes activated or repressed (by having a ratio ≥ ± 2.5-fold) by ArcA.

cBolded functional gene catagories contain a summary of the unbolded COG functional gene groups that are located in each of the previous lines.

Evans et al. BMC Microbiology 2011 11:58   doi:10.1186/1471-2180-11-58

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