Figure 1.

Role of IMPDH and MPA in GMP biosynthesis. MPA inhibits IMPDH. MPA: Mycophenolic acid. R: ribose 5'-monophosphate. IMP: inosine-5'-monophosphate, XMP: xanthosine-5'-monophosphate, guanosine-5'-monophosphate. GMP: Guanosine monophosphate. IMPDH: IMP dehydrogenase.

Hansen et al. BMC Microbiology 2011 11:202   doi:10.1186/1471-2180-11-202
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