Table 5

SNP and antibiotic resistance gene profiles of E. faecium isolates and their corresponding Sequence types (STs)

SNP Profile

SNP ID

No. of Isolates

Antibiotic resistance [Identified genetic determinants]

Corresponding sequence Types (STs) for SNP profiles in MLST


AAACTTTC

1

3

No antibiotic resistance detected

ST 544, ST 583

    AACCCTTCa

    2

1

Amp R [pbp5]m; Tet R [tetM]

ST 602 N

    AACCCTTCa

    2

3

Cip IR [gyrA]

    AACCCTTCa

    2

2

No antibiotic resistance detected

AATCCTTC

3

1

Gen IR [aac(6')-aph(2')]; Cip IR [gyrA]

ST8, ST9, ST58, ST134, ST194, ST198, ST237, ST244, ST248,

AATCCTTC

3

2

No antibiotic resistance detected

ST259, ST266, ST298, ST309, ST370, ST402, ST425,

AATCTTTC

4

1

No antibiotic resistance detected

ST40, ST100, ST163, ST211, ST221, ST223, ST226,

AGCCCCTC

5

1

Gen IR [aac(6')-aph(2')]

ST 607 N

AGCCCTCT

6

1

No antibiotic resistance detected

ST508

AGCCCTTT

7

2

Cip IR [gyrA]

ST 603 N

AGCCCTTT

7

1

No antibiotic resistance detected

    AGCCTTTC

    8

2

No antibiotic resistance detected

ST 604 N

    AGCTCTCC

    9

2

Gen IR [aac(6')-aph(2')];Cip R [gyrA]m;Amp R [pbp5]m

ST260, ST262, ST273, ST322

AGTCCTTC

10

2

Gen IR [aac(6')-aph(2')]; Cip R [gyrA]m

ST13, ST14, ST48, ST79, ST82, ST120, ST157, ST195, ST200, ST241

Tet R [tetL & S]

ST242, ST310, ST311,

AGTCCTTT

11

1

Gen IR [aac(6')-aph(2')]; Cip IR [gyrA]

ST15, ST70

AGTCTTTT

12

2

Cip IR [gyrA]

ST 605 N

GACCCTCC

13

1

Gen IR [aac(6')-aph(2')]

ST 608 N

GACCCTCC

13

1

Cip IR [gyrA]

GACCCTTT

14

1

Cip IR [gyrA]; Tet R [tetL & M]

ST 609 N

GACCCTTT

14

2

Tet R [tetL,M & S]

GATCCTTC

15

1

Gen IR [aac(6')-aph(2')]

ST 610 N

    GGCCCCCC

    16

2

Cip IR [gyrA]

ST501, ST511, ST516, ST518, ST521, ST522, ST529, ST530, ST565, ST588, ST592, ST599


    GGCCCTCC

    17

3

Amp R [pbp5]m; Tet IR [tetL & tetM]

ST162

GGCCCTTC

18

2

Cip IR [gyrA]

ST 611 N

GGCCTCCC

19

1

No antibiotic resistance detected

ST 606 N

GGTCCCCC

20

2

Cip IR [gyrA]

ST22, ST23, ST24, ST27, ST28, ST33, ST36, ST55, ST59, ST106,

ST111, ST119, ST122, ST131, ST136, ST159, ST214, ST263, ST269,

ST270, ST315, ST372, ST379, ST422, ST435

GGTCCTCC

21

1

Cip R [gyrA]m

ST1, ST2, ST3, ST4, ST32, ST34, ST35, ST41, ST43, ST72,

ST87, ST90, ST104, ST109, ST128, ST139, ST146, ST215, ST250, ST253

ST257, ST291, ST292, ST330, ST426, ST427,

GGTCCTTT

22

1

Cip IR [gyrA]

ST6, ST88, ST149, ST170, ST247, ST255, ST354

GGTCCTTC

23

2

No antibiotic resistance detected

ST7, ST21, ST25, ST26, ST29, ST37, ST57, ST66, ST68, ST83,

ST89,ST97,ST99,ST112,ST113,ST115,ST124, ST129, ST143, ST158,

ST160, ST176, ST183, ST210, ST236, ST243, ST245, ST246, ST251,

ST265, ST271, ST272, ST277, ST281, ST284, ST297, ST358, ST381,

ST384, ST395, ST401, ST418, ST433, ST437,


aSNP profiles which were present in hospital isolates are bold and underlined

SNP profiles in bold text are isolates with the same SNP profiles but with different antibiotic resistant gene profiles.

Amp; ampicillin, Cip; ciprofloxacin, Gen; gentamicin, Tet; tetracycline,

R Resistant, IR Intermediate resistant, m mutation

N New sequence types identified in the present study

Rathnayake et al. BMC Microbiology 2011 11:201   doi:10.1186/1471-2180-11-201

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