Table 1

Genes with significant differential expression in three L. sakei strains grown on ribose compared with glucose, FDR adjusted p-value less than 0.01 and log2 of > 0.5 or < -0.5 (log2 values > 1.0 or < -1.0 are shown in bold).

Gene locus

Gene

Description

23K

MF1053

LS 25


Carbohydrate transport and metabolism

Transport/binding of carbohydrates

LSA0185*

galP

Galactose:cation symporter

1.2

1.7

LSA0200*

rbsU

Ribose transport protein

2.8

3.5

4.3

LSA0353*

lsa0353

Putative cellobiose-specific PTS, enzyme IIB

3.6

1.3

2.5

LSA0449*

manL

Mannose-specific PTS, enzyme IIAB

2.1

2.5

1.5

LSA0450*

manN

Mannose-specific PTS, enzyme IIC

1.9

2.0

1.4

LSA0451*

manM

Mannose-specific PTS, enzyme IID

2.4

1.0

2.1

LSA0651*

glpF

Glycerol uptake facilitator protein, MIP family

3.4

4.7

3.4

LSA1050*

fruA

Fructose-specific PTS, enzyme IIABC

0.9

LSA1204*

lsa1204

Putative sugar transporter

1.1

LSA1457*

lsa1457

Putative cellobiose-specific PTS, enzyme IIC

2.3

LSA1462*

ptsI

PTS, enzyme I

0.8

1.7

0.9

LSA1463*

ptsH

Phosphocarrier protein HPr (histidine protein)

1.2

0.9

LSA1533

lsa1533

Putative cellobiose-specific PTS, enzyme IIA

2.5

2.1

LSA1690

lsa1690

Putative cellobiose-specific PTS, enzyme IIC

0.9

LSA1792*

scrA

Sucrose-specific PTS, enzyme IIBCA

0.8

1.1

Metabolism of carbohydrates and related molecules

LSA0123*

lsa0123

Putative sugar kinase, ROK family

1.2

LSA0198

ack1

Acetate kinase (acetokinase)

1.7

1.3

LSA0254*

lsa0254

Putative carbohydrate kinase

2.4

0.8

1.8

LSA0292*

budC

Acetoin reductase (acetoin dehydrogenase) (meso-2,3-butanediol dehydrogenase)

3.4

2.3

3.4

LSA0444

lsa0444

Putative malate dehydrogenase

3.4

D

2.1

LSA0516

hprK

Hpr kinase/phosphorylase

2.0

1.6

1.2

LSA0664*

loxL1N

L-lactate oxidase (N-terminal fragment), degenerate

1.2

0.7

LSA0665*

loxLI

L-lactate oxidase (central fragment), degenerate

1.0

LSA0666*

loxL1C

L-lactate oxidase (C-terminal fragment), degenerate

1.0

LSA0974*

pflB

Formate C-acetyltransferase (pyruvate formate-lyase) (formate acetyltransferase)

4.0

LSA0981

aldB

Acetolactate decarboxylase (alpha-acetolactate decarboxylase)

0.6

1.9

LSA0982

als

Acetolactate synthase (alpha-acetolactate synthase)

1.9

LSA0983

lsa0983

Putative aldose-1 epimerase

0.6

LSA1032

pyk

Pyruvate kinase

-0.7

LSA1080

lsa1080

Myo-inositol monophosphatase

0.6

0.8

    LSA1082

pdhD

Pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase

2.8

2.5

2.1

LSA1083

pdhC

Puruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase

3.4

3.7

2.7

    LSA1084

pdhB

Pyruvate dehydrogenase complex, E1 component, beta subunit

3.2

3.3

2.2

LSA1085

pdhA

Pyruvate dehydrogenase complex, E1 component, alpha subunit

2.9

3.5

2.4

LSA1141*

ppdK

Pyruvate phosphate dikinase

1.0

0.9

    LSA1188
*

pox1

Pyruvate oxidase

2.3

3.1

2.1

LSA1298

ack2

Acetate kinase (acetokinase)

1.1

0.9

0.9

LSA1343*

eutD

Phosphate acetyltransferase (phosphotransacetylase)

2.0

1.0

1.6

LSA1381

lsa1381

Putative acylphosphatase

-0.6

-0.5

LSA1399*

loxL2

L-lactate oxidase

3.4

U

LSA1630

lsa1630

Putative sugar kinase, ROK family

-0.6

-0.6

LSA1640*

nanA

N-acetylneuraminate lyase

2.0

D

LSA1641*

nanE

N-acylglucosamine/mannosamine-6-phosphate 2-epimerase

0.9

D

LSA1643*

lsa1643

Putative sugar kinase, ROK family

1.8

LSA1668

ack3

Acetate kinase (acetokinase)

-0.7

-1.1

    LSA1830
*

pox2

Pyruvate oxidase

0.7

Intermediary metabolism

LSA0255*

lsa0255

Putative phosphoribosyl isomerase

2.0

1.0

1.6

Specific carbohydrate metabolic pathway

    LSA0201
*

rbsD

D-ribose pyranase

2.5

2.5

3.4

    LSA0202
*

rbsK

Ribokinase

3.0

3.9

4.3

    LSA0289
*

xpk

Xylulose-5-phosphate phosphoketolase

3.2

2.3

2.6

LSA0297

gntZ

6-phosphogluconate dehydrogenase

-1.2

-0.9

-1.7

LSA0298

gntK

Gluconokinase

-0.8

LSA0381

zwf

Glucose-6-phosphate 1-dehydrogenase

-0.6

-0.6

-0.6

    LSA0649
*

glpK

Glycerol kinase

3.4

4.8

2.1

    LSA0650
*

glpD

Glycerol-3-phosphate dehydrogenase

2.3

2.2

2.0

LSA0764*

galK

Galactokinase

1.1

0.7

1.8

LSA0765*

galE1

UDP-glucose 4-epimerase

1.2

LSA0766*

galT

Galactose-1-phosphate uridylyltransferase

1.2

0.8

2.0

LSA0767*

galM

Aldose 1-epimerase (mutarotase)

1.3

2.0

LSA1146*

manA

Mannose-6-phosphate isomerase

1.4

1.3

1.5

LSA1531

lsa1531

Putative beta-glucosidase

0.7

0.9

LSA1588

nagA

N-acetylglucosamine-6-phosphate deacetylase

0.6

LSA1685

rpiA

Ribose 5-phosphate epimerase (ribose 5-phosphate isomerase)

1.1

0.8

LSA1710*

lacM

Beta-galactosidase, small subunit (lactase, small subunit)

3.3

1.2

LSA1711*

lacL

Beta-galactosidase, large subunit (lactase, large subunit)

3.0

1.5

1.7

LSA1790*

scrK

Fructokinase

1.0

1.1

LSA1791*

dexB

Glucan 1,6-alpha-glucosidase (dextran glucosidase)

1.1

LSA1795

melA

Alpha-galactosidase (melibiase)

-0.6

Glycolytic pathway

LSA0131

gpm2

Phosphoglycerate mutase

0.7

    LSA0206

gpm3

Phosphoglycerate mutase

-0.7

-0.8

-0.9

LSA0609*

gloAC

Lactoylglutathione lyase (C-terminal fragment), authentic frameshift

1.1

0.7

LSA0803

gpm4

Phosphoglycerate mutase

0.5

0.5

    LSA1033

pfk

6-phosphofructokinase

-0.6

-1.1

-0.5

LSA1157

mgsA

Methylglyoxal synthase

2.3

1.4

1.7

LSA1179

pgi

Glucose-6-phosphate isomerase

0.5

    LSA1527

fba

Fructose-bisphosphate aldolase

-1.0

-0.7

-1.1

    LSA1606

ldhL

L-lactate dehydrogenase

-1.0

-0.9

-1.5

Nucleotide transport and metabolism

Transport/binding of nucleosides, nucleotides, purines and pyrimidines

LSA0013

lsa0013

Putative nucleobase:cation symporter

-0.9

-1.5

LSA0055

lsa0055

Putative thiamine/thiamine precursor:cation symporter

1.6

LSA0064

lsa0064

Putative nucleobase:cation symporter

-0.8

LSA0259

lsa0259

Pyrimidine-specific nucleoside symporter

1.5

1.3

LSA0798*

lsa0798

Pyrimidine-specific nucleoside symporter

3.5

2.2

1.7

LSA0799*

lsa0799

Putative purine transport protein

4.4

2.7

2.9

LSA1210

lsa1210

Putative cytosine:cation symporter (C-terminal fragment), authentic frameshift

-0.8

-0.6

LSA1211

lsa1211

Putative cytosine:cation symporter (N-terminal fragment), authentic frameshit

-1.1

-0.9

Metabolism of nucleotides and nucleic acids

LSA0010

lsa0010

Putative nucleotide-binding phosphoesterase

-0.6

LSA0023

lsa0023

Putative ribonucleotide reductase (NrdI-like)

-0.5

D

D

LSA0063

purA

Adenylosuccinate synthetase (IMP-aspartate ligase)

-0.8

LSA0139

guaA

Guanosine monophosphate synthase (glutamine amidotransferase)

-0.5

-0.8

LSA0252

iunH1

Inosine-uridine preferring nucleoside hydrolase

2.6

2.6

1.8

LSA0446

pyrDB

Putative dihydroorotate oxidase, catalytic subunit

0.9

LSA0489

lsa0489

Putative metal-dependent phosphohydrolase precursor

0.5

LSA0533*

iunH2

Inosine-uridine preferring nucleoside hydrolase

1.2

LSA0785

lsa0785

Putative NCAIR mutase, PurE-related protein

-2.3

-1.3

LSA0795*

deoC

2 Deoxyribose-5 phosphate aldolase

4.0

2.1

2.2

LSA0796*

deoB

Phosphopentomutase (phosphodeoxyribomutase)

5.5

4.1

3.2

LSA0797*

deoD

Purine-nucleoside phosphorylase

4.5

2.6

1.9

LSA0801*

pdp

Pyrimidine-nucleoside phosphorylase

1.8

LSA0940

nrdF

Ribonucleoside-diphosphate reductase, beta chain

1.0

0.6

LSA0941

nrdE

Ribonucleoside-diphosphate reductase, alpha chain

1.0

0.6

LSA0942

nrdH

Ribonucleotide reductase, NrdH-redoxin

1.1

LSA0950

pyrR

Bifunctional protein: uracil phosphoribosyltransferase and pyrimidine operon transcriptional regulator

-0.6

LSA0993

rnhB

Ribonuclease HII (RNase HII)

0.6

LSA1018

cmk

Cytidylate kinase

0.6

LSA1097

lsa1097

Putative ADP-ribose phosphorylase, NUDIX family

0.5

LSA1352

lsa1352

Putative phosphomethylpyrimidine kinase

-0.8

LSA1651

lsa1651

Putative purine phosphoribosyltransferase, PRT family

0.8

LSA1661

lsa1661

Putative nucleotide hydrolase, NUDIX family

-0.5

LSA1805

dgk

Deoxyguanosine kinase

-1.0

-0.8

Transcription

Transcription regulation

LSA0130

lsa0130

Putative transcriptional regulator, LacI family

-0.6

LSA0132

lsa0132

Putative transcriptional regulator, MarR family

-0.6

LSA0161

lsa0161

Putative transcriptional regulator, ArsR family

-0.6

LSA0186

lsa0186

Putative transcriptional regulator, LytR family

0.8

0.6

LSA0203

rbsR

Ribose operon transcriptional regulator, LacI family

1.7

LSA0217

lsa0217

Putative thiosulfate sulfurtransferase with a ArsR-HTH domain, rhodanese family

-1.0

-0.7

LSA0229

lsa0229

Putative transcriptional regulator, MerR family (N-terminal fragment), authentic frameshift

-0.5

LSA0269

lsa0269

Putative transcriptional regulator, TetR family

-0.6

LSA0293

lsa0293

Putative DNA-binding protein, XRE family

-0.6

LSA0356

rex1

Redox-sensing transcriptional repressor, Rex

-0.8

-0.5

-0.9

LSA0603

cggR

Glycolytic genes regulator

-0.6

-0.6

LSA0669

lsa0669

Putative transcription regulator, TetR family

-0.6

LSA0783

lsa0783

Putative transcriptional regulator, Fnr/Crp Family

-0.6

LSA0800

deoR

Deoxyribonucleoside synthesis operon transcriptional regulator, GntR family

3.8

2.1

1.9

LSA0835

lsa0835

Putative DNA-binding protein, XRE family

-0.6

LSA0848

rex

Redox-sensing transcriptional repressor, Rex

1.6

0.7

LSA0972

lsa0972

Putative transcriptional regulator, LysR family

0.9

LSA1201

lsa1201

Putative transcriptional regulator, GntR family

1.4

D

D

LSA1322

glnR

Glutamine synthetase transcriptional regulator, MerR family

-1.4

-1.3

LSA1351

lsa1351

Putative transcritional regulator with aminotransferase domain, GntR family

-0.5

-0.6

LSA1434

lsa1434

Putative transcriptional regulator, DUF24 family (related to MarR/PadR families)

-0.8

LSA1449

spxA

Transcriptional regulator Spx

1.0

0.6

LSA1521

lsa1521

Putative transcriptional regulator, TetR family

0.6

LSA1554

lsa1554

Putative transcriptional regulator, LacI family

-0.7

-0.9

-0.5

LSA1587

lsa1587

Putative transcriptional regulator, GntR family

0.6

LSA1611

lsa1611

Putative DNA-binding protein, PemK family

-0.5

-0.7

LSA1653

lsa1653

Putative transcriptional regulator, MarR family

-0.6

LSA1692

lsa1692

Putative transcriptional regulator, GntR family

0.7

0.7

CoEnzyme transport and metabolism

Metabolism of coenzymes and prostethic groups

LSA0041

panE

2-dehydropantoate 2-reductase

0.8

LSA0057

thiE

Thiamine-phosphate pyrophosphorylase (thiamine-phosphate synthase)

1.9

LSA0058

thiD

Phosphomethylpyrimidine kinase (HMP-phosphate kinase)

1.4

LSA0059

thiM

Hydroxyethylthiazole kinase (4-methyl-5-beta-hydroxyethylthiazole kinase)

1.0

1.8

LSA0183

lsa0183

Putative hydrolase, isochorismatase/nicotamidase family

-0.7

LSA0840

lsa0840

Putative glutamate-cysteine ligase

0.6

LSA0947

fhs

Formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase)

0.6

LSA0980

lsa0980

Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, PfkB family

0.6

LSA1101

folK

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

0.6

U

LSA1614

acpS

Holo-[acyl-carrier protein] synthase (holo-ACP synthase) (4'-phosphopantetheine transferase AcpS)

-1.0

-0.9

-0.9

LSA1664

lsa1664

Putative dihydrofolate reductase

1.6

1.1

1.5

Energy production and conversion

Membrane bioenergetics (ATP synthase)

LSA1125

atpC

H(+)-transporting two-sector ATPase (ATP synthase), epsilon subunit

0.6

LSA1126

atpD

H(+)-transporting two-sector ATPase (ATP synthase), beta subunit

0.6

LSA1127

atpG

H(+)-transporting two-sector ATPase (ATP synthase), gamma subunit

0.8

LSA1128

atpA

H(+)-transporting two-sector ATPase (ATP synthase), alpha subunit

0.6

LSA1129

atpH

H(+)-transporting two-sector ATPase (ATP synthase), delta subunit

0.6

LSA1130

atpF

H(+)-transporting two-sector ATPase (ATP synthase), B subunit

0.5

LSA1131

atpE

H(+)-transporting two-sector ATPase (ATP synthase), C subunit

0.7

Inorganic ion transport and metabolism

Transport/binding of inorganic ions

LSA0029

lsa0029

Putative ion Mg(2+)/Co(2+) transport protein, hemolysinC-family

-0.7

LSA0134

lsa0134

Putative Na(+)/H(+) antiporter

-0.6

LSA0180

mtsC

Manganese ABC transporter, ATP-binding subunit

-0.8

LSA0181

mtsB

Manganese ABC transporter, membrane-spanning subunit

-0.8

-1.0

LSA0182

mtsA

Manganese ABC transporter, substrate-binding lipoprotein precursor

-0.7

-0.6

LSA0246

mntH1

Mn(2+)/Fe(2+) transport protein

-0.9

-1.3

LSA0283

lsa0283

Putative zinc/iron ABC transporter, ATP-binding subunit

-0.5

LSA0284

lsa0284

Putative zinc/iron ABC transporter, membrane-spanning subunit

-0.6

LSA0399

lsa0399

Iron(III)-compound ABC transporter, substrate-binding lipoprotein precursor

1.1

0.9

LSA0400

lsa0400

Iron(III)-compound ABC transporter, ATP-binding subunit

0.7

LSA0401

lsa0401

Iron(III)-compound ABC transporter, membrane-spanning subunit

0.5

LSA0402

lsa0402

Iron(III)-compound ABC transporter, membrane-spanning subunit

0.5

0.6

LSA0503

pstC

Phosphate ABC transporter, membrane-spanning subunit

0.5

LSA0504

pstA

Phosphate ABC transporter, membrane-spanning subunit

0.6

LSA0781

lsa0781

Putative cobalt ABC transporter, membrane-spanning/permease subunit

-0.9

LSA0782

lsa0782

Putative cobalt ABC transporter, membrane-spanning/permease subunit

-2.1

LSA1166

lsa1166

Putative potassium transport protein

0.7

LSA1440

cutC

Copper homeostasis protein, CutC family

-0.6

LSA1460

atkB

Copper-transporting P-type ATPase

0.6

LSA1638

lsa1638

Putative large conductance mechanosensitive channel

-1.0

-0.8

LSA1645

lsa1645

Putative Na(+)/(+) antiporter

1.4

D

LSA1699

mntH2

Mn(2+)/Fe(2+) transport protein

-0.6

LSA1703

lsa1703

Putative Na(+)/H(+) antiporter

-1.2

LSA1704

lsa1704

Putative calcium-transporting P-type ATPase

-0.8

LSA1735

lsa1735

Putative cobalt ABC transporter, membrane-spanning subunit

-0.6

LSA1736

lsa1736

Putative cobalt ABC transporter, ATP-binding subunit

-0.6

LSA1737

lsa1737

Putative cobalt ABC transporter, ATP-binding subunit

-0.7

LSA1838

lsa1838

Putative metal ion ABC transporter, membrane-spanning subunit

-0.5

LSA1839

lsa1839

Putative metal ion ABC transporter, substrate-binding lipoprotein precursor

-0.6

Amino acid transport and metabolism

Transport/binding of amino acids

LSA0125

lsa0125

Putative amino acid/polyamine transport protein

0.6

LSA0189

lsa0189

Putative amino acid/polyamine transport protein

-0.7

LSA0311

lsa0311

Putative glutamate/aspartate:cation symporter

-1.1

-1.0

LSA1037

lsa1037

Putative amino acid/polyamine transport protein

1.0

0.8

0.5

LSA1219

lsa1219

Putative cationic amino acid transport protein

0.7

LSA1415

lsa1415

Putative amino acid/polyamine transport protein

1.1

0.7

LSA1424

lsa1424

Putative L-aspartate transport protein

-1.4

-0.9

-1.2

LSA1435

lsa1435

Putative amino acid:H(+) symporter

1.0

0.8

LSA1496

lsa1496

Putative glutamine/glutamate ABC transporter, ATP-binding subunit

1.2

LSA1497

lsa1497

Putative glutamine/glutamate ABC transporter, membrane-spanning/substrate-binding subunit precursor

0.7

Transport/binding of proteins/peptides

LSA0702

oppA

Oligopeptide ABC transporter, substrate-binding lipoprotein precursor

1.3

1.0

LSA0703

oppB

Oligopeptide ABC transporter, membrane-spanning subunit

0.8

0.8

LSA0704

oppC

Oligopeptide ABC transporter, membrane-spanning subunit

1.8

1.0

LSA0705

oppD

Oligopeptide ABC transporter, ATP-binding subunit

1.2

1.1

LSA0706

oppF

Oligopeptide ABC transporter, ATP-binding subunit

1.2

1.2

Protein fate

LSA0053

pepO

Endopeptidase O

0.6

LSA0133

pepR

Prolyl aminopeptidase

1.5

LSA0226

pepN

Aminopeptidase N (lysyl-aminopeptidase-alanyl aminopeptidase)

-0.7

LSA0285

pepF1

Oligoendopeptidase F1

-0.7

LSA0320

pepD3

Dipeptidase D-type (U34 family)

-0.8

-0.5

LSA0424

pepV

Xaa-His dipeptidase V (carnosinase)

1.6

LSA0643

pepX

X-Prolyl dipeptidyl-aminopeptidase

0.6

LSA0888

pepT

Tripeptide aminopeptidase T

0.6

LSA1522

pepS

Aminopeptidase S

0.5

LSA1686

pepC1N

Cysteine aminopeptidase C1 (bleomycin hydrolase) (N-terminal fragment), authentic frameshift

1.6

LSA1688

pepC2

Cysteine aminopeptidase C2 (bleomycin hydrolase)

0.7

LSA1689

lsa1689

Putative peptidase M20 family

1.0

1.1

Metabolism of amino acids and related molecules

LSA0220_c

dapE

Succinyl-diaminopimelate desuccinylase

-1.4

-1.5

LSA0316

sdhB

L-serine dehydratase, beta subunit (L-serine deaminase)

-0.7

LSA0370*

arcA

Arginine deiminase (arginine dihydrolase)

1.9

LSA0372*

arcC

Carbamate kinase

0.5

LSA0463

lsa0463

Putative 2-hydroxyacid dehydrogenase

-0.7

LSA0509

kbl

2-amino-3-ketobutyrate coenzyme A ligase (glycine acetyltransferase)

1.5

LSA0510

lsa0510

L-threonine dehydrogenase (N-terminal fragment), authentic frameshift

2.0

0.5

LSA0572*

tdcB

Threonine deaminase (threonine ammonia-lyase, threonine dehydratase, IlvA homolog)

2.2

1.7

LSA0922

serA

D-3-phosphoglycerate dehydrogenase

0.9

LSA1134

glyA

Glycine/Serine hydroxymethyltransferase

0.7

LSA1321

glnA

Glutamate-ammonia ligase (glutamine synthetase)

-1.3

-1.0

LSA1484

mvaS

Hydroxymethylglutaryl-CoA synthase

-0.7

-0.6

-0.7

LSA1693

asnA2

L-asparaginase

0.8

Lipid transport and metabolism

Metabolism of lipids

LSA0045

cfa

Cyclopropane-fatty-acyl-phospholipid synthase

-1.3

-1.4

-1.4

LSA0644

lsa0644

Putative acyl-CoA thioester hydrolase

0.6

LSA0812

fabZ1

(3R)-hydroxymyristoyl-[acyl-carrier protein] dehydratase

-0.7

0.5

LSA0813

fabH

3-oxoacyl-[acyl carrier protein] synthetase III

0.6

LSA0814

acpP

Acyl carrier protein

0.6

LSA0815

fabD

Malonyl-CoA:ACP transacylase

-0.7

0.7

LSA0816

fabG

3-oxoacyl-acyl carrier protein reductase

-0.7

LSA0817

fabF

3-oxoacyl-[acyl carrier protein] synthetase II

-0.7

LSA0819

fabZ

(3R)-hydroxymyristoyl-[acyl carrier proetin] dehydratase

0.7

LSA0820

accC

Acetyl-CoA carboxylase (biotin carbooxylase subunit)

-0.7

LSA0821

accD

Acetyl-CoA carboxylase (carboxyl transferase beta subunit)

0.8

LSA0822

accA

Acetyl-CoA carboxylase (carboxyl transferase alpha subunit)

0.6

LSA0823

fabI

Enoyl [acyl carrier protein] reductase

0.9

LSA0891

lsa0891

Putative lipase/esterase

1.2

LSA1485

mvaA

Hydroxymethylglutaryl-CoA reductase

-0.5

LSA1493

lsa1493

Putative diacylglycerol kinase

-0.6

-0.9

-0.7

LSA1652

ipk

4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

-0.6

-0.7

Secondary metabolites transport and metabolism

Transport/binding proteins and lipoproteins

LSA0046

lsa0046

Putative transport protein

-1.0

-0.6

-1.3

LSA0089

lsa0089

Putative drug transport protein

-2.1

-0.9

-0.8

LSA0094

lsa0094

Putative transport protein, Major Facilitator Super (MFS) family transporter

-0.7

-0.7

LSA0095

lsa0095

Putative transport protein

1.3

0.5

LSA0128

lsa0128

Putative antimicrobial peptide ABC exporter, membrane-spanning/permease subunit

-0.5

LSA0187

lsa0187

Putative drug-resistance ABC transporter, two ATP-binding subunits

0.7

LSA0219_b

lsa0219_b

Putative cyanate transport protein

-0.6

LSA0232

lmrA

Multidrug ABC exporter, ATP-binding and membrane-spanning/permease subunits

-0.7

-0.7

LSA0270

lsa0270

Putative multidrug ABC exporter, membrane-spanning/permease subunit

-0.7

LSA0271

lsa0271

Putative multidrug ABC exporter, ATP-binding subunit

-0.7

-0.6

LSA0272

lsa0272

Putative multidrug ABC exporter, ATP-binding and membrane-spanning/permease subunits

-0.6

-0.6

LSA0308

lsa0308

Putative drug:H(+) antiporter

-0.7

LSA0376

lsa0376

Putative transport protein

0.7

LSA0420

lsa0420

Putative drug:H(+) antiporter (N-terminal fragment), authentic frameshift

-0.8

-1.1

LSA0469

lsa0469

Putative drug:H(+) antiporter

-0.6

-0.5

LSA0788

lsa0788

Putative facilitator protein, MIP family

-2.6

LSA0936

lsa0936

Putative drug ABC exporter, membrane-spanning/permease subunit

1.1

LSA0937

lsa0937

Putative drug ABC exporter, membrane-spanning/permease subunit

1.3

LSA0938

lsa0938

Putative drug ABC exporter, ATP-binding subunit

1.2

LSA0963

lsa0963

Integral membrane protein, hemolysin III related

LSA1088

lsa1088

Putative multidrug ABC exporter, ATP-binding and membrane-spanning/permease subunits

0.5

LSA1261

lsa1261

Putative autotransport protein

0.5

LSA1340

lsa1340

Putative transport protein

-0.7

LSA1366

lsa1366

Putative ABC exporter, ATP-binding subunit

-0.8

-1.0

LSA1367

lsa1367

Putative ABC exporter, membrane-spanning/permease subunit

-0.8

-0.5

-0.8

LSA1420

lsa1417

Putative lipase/esterase

-1.1

LSA1621

lsa1621

Putative drug:H(+) antiporter

-1.1

LSA1642

lsa1642

Putative Solute:Na(+) symporter

3.4

1.8

D

LSA1872

lsa1872

Putative drug:H(+) antiporter

0.7

LSA1878

lsa1878

Putative drug resistance ABC transporter, two ATP-binding subunits

-0.6

Detoxification

LSA0772

lsa0772

Hypothetical protein (TelA, telluric resistance family)

1.0

0.7

LSA1317

lsa1317

Putative chromate reductase

0.6

-0.7

LSA1450

lsa1450

Putative metal-dependent hydrolase (beta-lactamase family III)

0.6

LSA1776

lsa1776

Putative 4-carboxymuconolactone decarboxylase

0.6

D

Translation, ribosomal structure and biogenesis

Translation initiation

LSA1135

lsa1135

Putative translation factor, Sua5 family

0.7

0.6

Translation elongation

LSA0251

efp1

Elongation factor P (EF-P)

0.5

LSA1063

tuf

Elongation factor Tu (EF-Tu)

0.6

Ribosomal proteins

LSA0011

rplI

50S Ribosomal protein L9

-0.8

LSA0266

rpsN

30S ribosomal protein S14

0.7

-0.5

LSA0494

lsa0494

30S ribosomal interface protein S30EA

1.7

LSA0696

rpmB

50S ribosomal protein L28

0.8

LSA1017

rpsA

30S Ribosomal protein S1

0.9

0.6

LSA1333

rpmG

50S ribosomal protein L33

0.6

LSA1666

rplL

50S ribosomal protein L7/L12

-0.6

LSA1676

rpmG2

50S ribosomal protein L33

-0.6

LSA1750

rplF

50S ribosomal protein L6

0.6

LSA1755

rpsQ

30S ribosomal protein S17

0.5

LSA1761

rplB

50S ribosomal protein L2

0.6

LSA1765

rpsJ

30S ribosomal protein S10

-0.7

Protein synthesis

LSA0377

tgt

Queuine tRNA-ribosyltransferase

-0.6

LSA1546

gatB

Glutamyl-tRNA amidotransferase, subunit B

-0.5

LSA1547

gatA

Glutamyl-tRNA amidotransferase, subunit A

-0.5

-0.5

RNA restriction and modification

LSA0437

lsa0437

Hypothetical protein with an RNA-binding domain

-0.7

LSA0443

lsa0443

Putative single-stranded mRNA endoribonuclease

2.7

1.9

LSA0738

dtd

D-tyrosyl-tRNA(tyr) deacylase

0.5

LSA0794

trmU

tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase

-0.9

LSA1534

lsa1534

Putative ATP-dependent RNA helicase

0.9

LSA1615

lsa1615

Putative ATP-dependent RNA helicase

-0.7

-0.8

-1.0

LSA1723

truA

tRNA pseudouridylate synthase A (pseudouridylate synthase I)

-0.7

-0.6

LSA1880

trmE

tRNA modification GTPase trmE

-0.7

Aminoacyl-tRNA synthetases

LSA0880

glyQ

Glycyl-tRNA synthetase, alpha subunit

0.7

LSA0881

glyS

Glycyl-tRNA synthetase, beta subunit

0.7

LSA1400

thrS

Threonyl-tRNA synthetase

0.6

LSA1681

cysS

Cysteinyl-tRNA synthetase

-0.6

DNA replication, recombination and repair

DNA replication

LSA0221

lsa0221

Putative transcriptional regulator, LysR family (C-terminal fragment), degenerate

-0.8

-0.9

-1.1

LSA0976

parE

Topoisomerase IV, subunit B

0.5

Transposon and IS

LSA1152_a

tnpA3-ISLsa1

Transposase of ISLsa1 (IS30 family)

-0.6

Phage-related function

LSA1292

lsa1292

Putative prophage protein

0.6

LSA1788

lsa1788

Putative phage-related 1,4-beta-N-acetyl muramidase (cell wall hydrolase)

-1.0

D

D

DNA recombination and repair

LSA0076

lsa0076

Putative DNA invertase (plasmidic resolvase)

-1.1

-1.5

-1.4

LSA0366

ruvA

Holliday junction DNA helicase RuvA

-0.5

LSA0382

dinP

DNA-damage-inducible protein P

-0.5

LSA0487

recA

DNA recombinase A

-0.8

-1.1

LSA0523

uvrB

Excinuclease ABC, subunit B

-0.7

-0.5

LSA0524

uvrA1

Excinuclease ABC, subunit A

-1.2

-0.7

LSA0910

rexAN

ATP-dependent exonuclease, subunit A (N-terminal fragment), authentic frameshift

0.6

LSA0911

rexAC

ATP-dependent exonuclease, subunit A (C-terminal fragment), authentic frameshift

0.7

LSA0912

lsa0912

Putative ATP-dependent helicase, DinG family

0.6

0.8

LSA1162

lsa1162

DNA-repair protein (SOS response UmuC-like protein)

0.8

-0.6

LSA1405

fpg

Formamidopyrimidine-DNA glycosylase

-0.5

-0.6

-0.6

LSA1477

recX

Putative regulatory protein, RecX family

-0.6

LSA1843

ogt

Methylated-DNA-protein-cysteine S-methyltransferase

-0.6

DNA restriction and modification

LSA0143

lsa0143

Putative adenine-specific DNA methyltransferase

-0.7

D

D

LSA0921

lsa0921

Putative adenine-specific DNA methyltransferase

0.8

LSA1299

lsa1299

Putative adenine-specific DNA methyltransferase

0.9

0.7

1.2

Information pathways

LSA0326

lsa0326

Putative DNA helicase

-0.6

U

DNA packaging and segregation

LSA0135

lsa0135

Hypothetical integral membrane protein, similar to CcrB

-0.6

LSA1015

hbsU

Histone-like DNA-binding protein HU

1.0

0.9

Cell division and chromosome partitioning

Cell division

LSA0755

divIVA

Cell-division initiation protein (septum placement)

0.5

LSA0845

lsa0845

Putative negative regulator of septum ring formation

0.7

0.6

LSA1118

lsa1118

Rod-shape determining protein

0.6

0.5

LSA1597

ftsH

ATP-dependent zinc metalloendopeptidase FtsH (cell division protein FtsH)

-0.6

LSA1879

gidA

Cell division protein GidA

-0.6

Cell envelope biogenesis, outer membrane

Cell wall

LSA0280

murE

UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase

-0.6

-0.6

-0.7

LSA0621

pbp2A

Bifunctional glycolsyltransferase/transpeptidase penicillin binding protein 2A

0.7

LSA0648

lsa0648

Putative penicillin-binding protein precursor (beta-lactamase class C)

1.0

LSA0862

lsa0862

N-acetylmuramoyl-L-alanine amidase precursor (cell wall hydrolase) (autolysin)

0.6

0.8

LSA0917

pbp1A

Bifunctional glycosyltransferase/transpeptidase penicillin-binding protein 1A

0.5

LSA1123

murA1

UDP-N-acetylglucosamine 1-carboxyvinyltransferase I

-0.5

LSA1334

pbp2B2

Bifuntional dimerisation/transpeptidase penicillin-binding protein 2B

0.7

0.7

LSA1437

lsa1437

N-acetylmuramoyl-L-alanine amidase precursor (cell wall hydrolase) (autolysin)

-0.7

LSA1441

bacA

Putative undecaprenol kinase (bacitracine resistance protein A)

0.6

LSA1613

alr

Alanine racemase

-0.8

-0.9

-0.7

LSA1616

murF

UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase

-0.5

Cell envelope and cellular processes

LSA0162

lsa0162

Putative Bifunctional glycosyl transferase, family 8

-1.2

-1.5

LSA1246

lsa1246

Putative glycosyl transferase, family 2

-0.9

LSA1558

lsa1558

Putative extracellular N-acetylmuramoyl-L-alanine amidase precursor (cell wall hydrolase/Lysosyme subfamily 2)

-0.6

Cell motility and secretion

Protein secretion

LSA0948

lspA

Signal peptidase II (lipoprotein signal peptidase) (prolipoprotein signal peptidase)

0.5

LSA1884

oxaA2

Membrane protein chaperone oxaA

-0.6

Signal transduction

Signal transduction

LSA0561

sppKN

Two-component system, sensor histidine kinase, (SppK fragment), degenerate

0.5

LSA0692

lsa0692

Putative serine/threonine protein kinase

0.5

0.6

LSA1384

lsa1384

Two-component system, response regulator

0.5

Post translational modifications, protein turnover, chaperones

Protein folding

LSA0050

lsa0050

Putative molecular chaperone, small heat shock protein, Hsp20 family

-0.7

LSA0082

htrA

Serine protease HtrA precursor, trypsin family

-0.6

LSA0207

clpL

ATPase/chaperone ClpL, putative specificity factor for ClpP protease

0.6

LSA0358

groS

Co-chaperonin GroES (10 kD chaperonin) (protein Cpn10)

-0.5

LSA0359

groEL

Chaperonin GroEL (60 kDa chaperonin) (protein Cpn60)

-0.5

LSA0436

lsa0436

Putative peptidylprolyl isomerase (peptidylprolyl cis-trans isomerase) (PPIase)

-0.6

LSA0984

hslU

ATP-dependent Hsl protease, ATP-binding subunit HslU

0.7

0.7

LSA1465

clpE

ATPase/chaperone ClpE, putative specificity factor for ClpP protease

-0.7

-0.6

-0.6

LSA1618

htpX

Membrane metalloprotease, HtpX homolog

0.8

Adaption to atypical conditions

LSA0170

lsa0170

Putative general stress protein

0.5

-1.5

LSA0247

usp2

Similar to universal stress protein, UspA family

-0.5

LSA0264

lsa0264

Putative glycine/betaine/carnitine/choline transport protein

-0.6

-0.6

LSA0513

lsa0513

Putative stress-responsive transcriptional regulator

-0.8

LSA0552

lsa0552

Organic hydroperoxide resistance protein

0.6

LSA0616

lsa0616

Putative glycine/betaine/carnitine/choline ABC transporter, ATP-binding subunit

0.9

LSA0617

lsa0617

Putative glycine/betaine/carnitine/choline ABC transporter, membrane-spanning subunit

1.3

LSA0618

lsa0618

Putative glycine/betaine/carnitine/choline ABC transporter, substrate-binding lipoprotein

0.6

LSA0619

lsa0619

Putative glycine/betaine/carnitine/choline ABC transporter, membrane-spanning subunit

1.5

0.5

LSA0642

usp3

Similar to universal stress protein, UspA

0.9

LSA0768

csp1

Similar to cold shock protein, CspA family

2.1

0.6

1.8

LSA0836

usp6

Similar to universal stress protein, UspA family

0.6

LSA0946

csp4

Similar to cold shock protein, CspA family

0.6

LSA1110

lsa1110

Putative NifU-homolog involved in Fe-S cluster assembly

0.6

LSA1111

lsa1111

Putative cysteine desulfurase (class-V aminotransferase, putative SufS protein homologue)

0.7

LSA1173

usp4

Similar to universal stress protein, UspA family

1.5

-2.1

LSA1694

lsa1694

Putative glycine/betaine/carnitine ABC transporter, substrate binding lipoprotein precursor

-1.7

-1.1

LSA1695

lsa1695

Putative glycine/betaine/carnitine ABC transporter, membrane-spanning subunit

-2.1

-2.0

-1.9

LSA1696

lsa1696

Putative glycine/betaine/carnitine ABC transporter, ATP-binding subunit

-1.6

-0.9

LSA1870

lsa1870

Putative glycine betaine/carnitine/choline ABC transporter, ATP-binding subunit

-0.6

-0.6

Protein modification

LSA0865

lsa0865

Putative protein methionine sulfoxide reductase

-0.6

LSA0866

msrA

Protein methionine sulfoxide reductase

-0.7

LSA0934

lplA

Lipoate-protein ligase

1.6

1.4

1.0

LSA0973

pflA

Pyruvate formate-lyase activating enzyme

1.7

General function prediction only

Miscellaneous

LSA0030

lsa0030

Putative aldo/keto reductase (oxidoreductase)

-0.7

-0.8

LSA0120

lsa0120

Putative GTP-binding protein

-0.5

LSA0164

lsa0164

Putative serine/tyrosine protein phosphatase

0.2

-1.1

-1.2

    LSA0165

lsa0165

Putative oxidoreductase, short chain dehydrogenase/reductase family

-0.9

-1.2

LSA0218

trxA1

Thioredoxin

-0.9

LSA0258

lsa0258

Putative iron-containing alcohol dehydrogenase

1.6

0.5

1.6

LSA0260

lsa0260

Putative aldo/keto reductase (oxidoreductase)

1.9

1.2

1.7

LSA0312

lsa0312

Putative NADH oxidase

-0.9

-1.0

LSA0324

lsa0324

Putative hydrolase, haloacid dehalogenase family (N-terminal fragment), authentic frameshift

1.9

LSA0325

lsa0325

Putative hydrolase, haloacid dehalogenase family (C-terminal fragment), authentic frameshift

1.8

LSA0350

lsa0350

Putative N-acetyltransferase, GNAT family

-0.5

LSA0369

lsa0369

Putative N-acetyltransferase, GNAT family

-0.5

-0.5

LSA0384

lsa0384

Putative phosphoesterase, DHH family

-0.5

LSA0403

lsa0403

Putative thioredoxin reductase

0.9

LSA0447

lsa0447

Putative hydrolase, haloacid dehalogenase family

0.6

LSA0475

lsa0475

Putative N-acetyltransferase, GNAT family

-0.6

LSA0520

trxB2

Thioredoxin reductase

-0.8

LSA0575

npr

NADH peroxidase

1.0

U

LSA0802

nox

NADH oxidase

1.5

LSA0806

lsa0806

Putative N-acetyltransferase, GNAT family

0.6

LSA0831

lsa0831

Putative nitroreductase (oxidoreductase)

1.6

LSA0896

sodA

Iron/Manganese superoxide dismutase

3.4

1.7

1.7

LSA0925

adh

Putative zinc-containg alcohol dehydrogenase (oxidoreductase)

0.5

LSA0971

ppa

Inorganic pyrophosphatase (pyrophosphate phosphohydrolase)

0.7

LSA0994

lsa0994

Putative GTP-binding protein

0.6

LSA1016

engA

Putative GTP-binding protein

0.6

0.7

LSA1045

obgE

Putative GTP-binding protein

0.6

LSA1153

lsa1153

Hypothetical protein, CAAX protease family

0.5

LSA1311

lsa1311

Hypothetical protein containing a possible heme/steroid binding domain

0.7

-0.6

LSA1320

lsa1320

Putative NADPH-quinone oxidoreductase

-0.8

LSA1345

lsa1345

Putative hydrolase, haloacid dehalogenase family

0.5

LSA1349

lsa1349

Putative N-acetyltransferase, GNAT family

-0.5

LSA1365

lsa1365

Hypothetical protein

-0.5

-0.7

LSA1368

lsa1368

Hypothetical protein

0.9

0.6

LSA1371

lsa1371

Hypothetical membrane protein

0.6

LSA1395

lsa1395

Putative zinc-containing alcohol dehydrogenase (oxidoreductase)

0.9

LSA1427

lsa1427

Putative hydrolase, haloacid dehalogenase

1.3

0.6

LSA1472

lsa1472

Putative N-acetyl transferase, GNAT family

0.6

LSA1535

lsa1535

Putative oxidoreductase

0.5

1.1

0.7

LSA1553

lsa1553

Putative hydrolase, haloacid dehalogenase family

-0.6

LSA1559

lsa1559

Putative oxidoreductase

0.6

1.1

0.7

LSA1702

lsa1702

Putative zinc-containing alcohol dehydrogenase (oxidoreductase)

1.1

LSA1712

lsa1712

Putative nitroreductase (oxidoreductase)

-0.7

-0.8

LSA1832

lsa1832

Putative zinc-containing alcohol dehydrogenase (oxidoreductase)

1.0

LSA1835

lsa1835

Putative zinc-containing alcohol dehydrogenase (oxidoreductase)

-0.7

-1.0

LSA1867

lsa1867

Putative acetyltransferase, isoleucine patch superfamily

-0.5

-0.6

-0.7

LSA1871

gshR

Glutathione reductase

-0.6

Unknown

Proteins of unknown function that are similar to other proteins

LSA0018

lsa0018

Hypothetical protein

0.5

LSA0027

lsa0027

Hypothetical protein

-1.1

LSA0028

lsa0028

Hypothetical protein, DegV family

-0.5

LSA0044

lsa0044

Hypothetical protein

-0.7

LSA0061

lsa0061

Hypothetical extracellular protein precursor

-0.5

LSA0106

lsa0106

Hypothetical cell surface protein precursor

0.5

LSA0160

lsa0160

Hypothetical protein

-0.7

LSA0166

lsa0166

Hypothetical Integral membrane protein

-1.2

LSA0190

lsa0190

Hypothetical integral membrane protein

-0.7

-0.6

LSA0191

lsa0191

Hypothetical integral membrane protein

-0.6

-0.6

LSA0199

lsa0199

Hypothetical protein

1.1

1.0

1.1

LSA0208

lsa0208

Hypothetical integral membrane protein

0.7

LSA0235

lsa0235

Hypothetical extracellular protein precursor

2.1

1.6

1.7

LSA0236

lsa0236

Hypothetical extracellular peptide precursor

2.0

1.3

1.5

LSA0244

lsa0244

Hypothetical integral membrane protein

-0.5

LSA0245

lsa0245

Hypothetical lipoprotein precursor

-0.9

-1.0

-1.1

LSA0249

lsa0249

Hypothetical protein

1.1

1.0

LSA0263

lsa0263

Hypothetical integral membrane protein

-0.6

-0.9

LSA0300

lsa0300

Hypothetical protein

0.7

LSA0315

lsa0315

Hypothetical protein

-0.7

LSA0319

lsa0319

Hypothetical protein

-0.8

-0.8

LSA0323

lsa0323

Hypothetical protein

-0.5

LSA0337

lsa0337

Hypothetical protein

-0.7

LSA0348

lsa0348

Hypothetical integral membrane protein

-0.9

-0.7

LSA0352

lsa0352

Hypothetical integral membrane protein

-0.6

LSA0354

lsa0354

Hypothetical integral membrane protein

-1.1

LSA0388

lsa0388

Hypothetical protein

-0.6

LSA0389

lsa0389

Hypothetical protein

-0.7

-0.7

LSA0390

lsa0390

Hypothetical protein

-0.5

LSA0409

lsa0409

Hypothetical integral membrane protein

-0.8

LSA0418

lsa0418

Hypothetical protein

-0.8

LSA0464

lsa0464

Hypothetical protein

-0.6

LSA0470

lsa0470

Hypothetical protein

0.9

0.7

LSA0512

lsa0512

Hypothetical protein

-0.6

LSA0515

lsa0515

Hypothetical integral membrane protein

-0.5

LSA0536

lsa0536

Hypothetical protein

0.7

LSA0716

lsa0716

Hypothetical protein

0.6

LSA0752

lsa0752

Hypothetical protein

0.5

0.6

LSA0757

lsa0757

Hypothetical protein

0.8

LSA0773

lsa0773

Hypothetical protein

0.9

0.6

LSA0784

lsa0784

Hypothetical protein

-2.6

LSA0786

lsa0786

Hypothetical protein

-2.0

LSA0787

lsa0787

Hypothetical protein

-1.7

LSA0790

lsa0790

Hypothetical protein, ATP utilizing enzyme PP-loop family

-2.5

LSA0827

lsa0827

Hypothetical lipoprotein precursor

0.8

U

LSA0828

lsa0828

Hypothetical protein

0.7

LSA0829

lsa0829

Hypothetical integral membrane protein

0.5

LSA0874

lsa0874

Hypothetical protein

0.5

LSA0901

lsa0901

Hypothetical protein

0.5

LSA0913

lsa0913

Hypothetical extracellular protein precursor

0.5

0.7

LSA0919

lsa0919

Hypothetical protein

0.7

LSA0933

lsa0933

Hypothetical protein

0.6

0.6

LSA0961

lsa0961

Hypothetical protein, DegV family

-0.5

LSA0968

lsa0968

Hypothetical integral membrane protein

0.7

LSA0977

lsa0977

Hypothetical integral membrane protein

0.7

0.8

LSA0987

lsa0987

Hypotehtical protein, GidA family (C-terminal fragment)

0.5

LSA0996

lsa0996

Hypothetical protein

0.5

LSA1003

lsa1003

Hypothetical protein

2.0

1.2

LSA1005

lsa1005

Hypothetical membrane protein

0.9

0.6

0.7

LSA1008

lsa1008

Putative extracellular chitin-binding protein precursor

0.9

1.2

LSA1027

lsa1027

Hypothetical protein

0.6

LSA1047

lsa1047

Hypothetical protein

3.5

1.2

1.3

LSA1064

lsa1064

Hypothetical protein

0.5

0.7

LSA1075

lsa1075

Hypothetical protein

0.5

LSA1078

lsa1078

Hypothetical protein

0.6

LSA1081

lsa1081

Hypothetical protein

1.0

1.0

LSA1091

lsa1091

Hypothetical protein

0.6

LSA1096

lsa1096

Hypothetical protein

0.6

LSA1124

lsa1124

Hypothetical protein

-0.7

LSA1154

lsa1154

Hypothetical protein

0.6

0.6

LSA1158

lsa1158

Hypothetical protein

1.7

1.4

LSA1189

lsa1189

Hypothetical integral membrane protein

-1.6

-1.1

LSA1282

lsa1282

Hypothetical protein

-0.5

LSA1296

lsa1296

Hypothetical integral membrane protein

-1.2

-0.8

LSA1342

lsa1342

Hypothetical protein

-0.7

LSA1346

lsa1346

Hypothetical protein

0.8

LSA1350

lsa1350

Hypothetical protein

-0.6

-1.0

LSA1353

lsa1353

Hypothetical integral membrane protein

-0.9

-0.5

LSA1446

lsa1446

Hypothetical protein

-0.6

-0.6

-0.7

LSA1466

lsa1466

Hypothetical protein

0.6

LSA1467

lsa1467

Hypothetical protein

-0.6

-1.1

LSA1524

lsa1524

Hypothetical protein

0.7

LSA1540

lsa1540

Hypothetical extracellular protein precursor

0.7

LSA1563

lsa1563

Hypothetical integral membrane protein

-0.6

-0.6

LSA1610

lsa1610

Hypothetical integral membrane protein

-0.7

-0.9

LSA1617

lsa1617

Hypothetical protein

-0.7

LSA1620

lsa1620

Hypothetical protein

-0.6

LSA1623

lsa1623

Hypothetical integral membrane protein

-0.5

-0.6

LSA1637

lsa1637

Hypothetical integral membrane protein, TerC family

-1.7

-1.0

-1.6

LSA1644

lsa1644

Hypothetical protein

1.7

D

LSA1649

lsa1649

Hypothetical extracellular protein precursor

-0.5

LSA1659

lsa1659

Hypothetical protein

-0.5

LSA1662

lsa1662

Hypothetical protein

-1.0

-0.6

-0.7

LSA1663

lsa1663

Hypothetical protein

-0.8

LSA1678

lsa1678

Hypothetical protein

-0.6

LSA1680

lsa1680

Hypothetical protein

-0.6

LSA1716

lsa1716

Hypothetical protein

-0.5

LSA1822

lsa1822

Hypothetical protein

-0.5

LSA1828

lsa1828

Hypothetical integral membrane protein

0.6

0.7

LSA1850

lsa1850

Hypothetical protein

-0.6

LSA1876

lsa1876

Hypothetical integral membrane protein

-0.6

LSA1877

lsa1877

Hypothetical protein

-0.6

Proteins of unknown function only similar to other proteins from the same organism

LSA1159

lsa1159

Hypothetical cell surface protein precursor

2.0

0.5

LSA1165

lsa1165

Hypothetical cell surface protein precursor

1.8

LSA1700

lsa1700

Hypothetical protein

2.1

0.8

LSA1814

lsa1814

Hypothetical protein

-0.5

Proteins of unknown function. without similarity to other proteins

LSA0065

lsa0065

Hypothetical integral membrane protein

-0.5

LSA0093

lsa0093

Hypothetical integral membrane protein

-0.9

-1.2

LSA0121

lsa0121

Hypothetical small peptide

-0.7

-0.6

-0.5

LSA0163

lsa0163

Hypothetical protein

-1.1

-1.3

LSA0167

lsa0167

Hypothetical protein

-1.4

LSA0168

lsa0168

Hypothetical protein

-1.4

LSA0188

lsa0188

Hypothetical small peptide

-0.8

LSA0256_a

lsa0256_a

Hypothetical protein

2.3

1.0

2.2

LSA0257

lsa0257

Hypothetical protein

1.4

LSA0281

lsa0281

Hypothetical lipoprotein precursor

-0.5

-0.6

LSA0301

lsa0301

Hypothetical protein

0.6

LSA0334

lsa0334

Hypothetical extracellular protein precursor

1.1

LSA0339

lsa0339

Hypothetical protein

-0.5

LSA0378

lsa0378

Hypothetical protein

-0.7

LSA0514

lsa0514

Hypothetical small extracellular protein precursor

-0.8

LSA0534

lsa0534

Hypothetical cell surface protein precursor (with LPQTG sorting signal)

1.0

D

LSA0576

lsa0576

Hypothetical protein

0.5

D

LSA0641

lsa0641

Hypothetical extracellular peptide precursor

-0.5

LSA0647

lsa0647

Hypothetical extracellular protein precursor

0.6

LSA0667

lsa0667

Hypothetical protein

1.0

0.9

LSA0753

lsa0753

Hypothetical integral membrane protein

0.5

LSA0789

lsa0789

Hypothetical protein

-1.9

LSA0837

lsa0837

Hypothetical protein

1.2

1.3

1.4

LSA0885

lsa0885

Hypothetical protein

1.8

LSA0902

lsa0902

Hypothetical protein

0.7

D

LSA0945

lsa0945

Hypothetical protein

0.9

LSA1019

lsa1019

Hypothetical cell surface protein precursor

0.8

LSA1035

lsa1035

Hypothetical small integral membrane protein

0.6

LSA1086

lsa1086

hypothetical protein

0.8

0.5

LSA1104

lsa1104

Hypothetical protein

-0.5

LSA1155

lsa1155

Hypothetical integral membrane protein

0.5

LSA1174

lsa1174

Hypothetical protein

1.0

LSA1176

lsa1176

Hypothetical protein

-1.0

U

LSA1319

lsa1319

Hypothetical small protein

-0.8

LSA1408

lsa1408

Hypothetical protein

0.6

LSA1464

lsa1464

Hypothetical protein

-0.6

LSA1478

lsa1478

Hypothetical protein

-0.7

-0.6

-0.6

LSA1480

lsa1480

Hypothetical membrane protein

0.5

D

LSA1524

lsa1524

Hypothetical protein

0.8

LSA1539

lsa1539

Hypothetical protein

0.9

LSA1713

lsa1713

Hypothtical small peptide

-0.6

LSA1787

lsa1787

Hypothetical cell surface protein precursor

-0.5

U

LSA1820

lsa1820

Hypothetical cell surface protein precursor

-0.6

LSA1821

lsa1821

Hypothetical cell surface protein precursor

-0.6

LSA1845

lsa1845

Hypothetical small protein

0.8

LSA1848

lsa1848

Hypothetical protein

-0.5

LSA1851

lsa1851

Hypothetical extracellular small protein

-0.6

-0.7

LSA1883

lsa1883

Hypothetical small protein

1.2

1.5

Bacteriocin associated genes

SKP0001

sppIP

Bacteriocin sakacin P inducing peptide

D

0.5

D

SKP0006

sppT

Sakacin P ABC transporter

D

0.6

D

SKP0007

sppE

Sakacin P accesory transport protein

D

0.6

D


The microarray used has been described previously [32]. Asterix (*) relates the gene to Table 2. D and U refer to genes classified as 'divergent' and 'uncertain', respectively, by CGH analysis [32]. Genes encoding proteins with a change in expression according to McLeod et al. [19], are underlined.

McLeod et al. BMC Microbiology 2011 11:145   doi:10.1186/1471-2180-11-145

Open Data