Table 1

Gene list of significantly up- and down-regulated genes in the HP0256 mutant based on the array experiment.

TIGR orf no.

Putative gene product (gene)

Expression ratio

p-value


Down-regulated genes:

Hp26695-0092

type II restriction enzyme M protein (hsdM)

0.15

0.02

HpJ99-1132

dimethyladenosine transferase

0.17

0.00

Hp26695-0093

alpha-2-fucosyltransferase

0.22

0.01

Hp26695-0229

outer membrane protein (omp6) (hopA)

0.24

0.01

Hp26695-0492

flagellar sheath associated protein (hpaA3)

0.26

0.00

Hp26695-1210

serine acetyltransferase (cysE)

0.26

0.00

Hp26695-1587

conserved hypothetical protein

0.27

0.00

Hp26695-1208

ulcer associated adenine specific DNA methyltransferase

0.27

0.00

Hp26695-0610

toxin-like outer membrane protein

0.32

0.03

Hp26695-1207

hypothetical protein

0.34

0.01

HpJ99-0055

putative

0.35

0.03

Hp26695-1211

hypothetical protein

0.37

0.00

Hp26695-0430

hypothetical protein

0.40

0.04

Hp26695-1492

conserved hypothetical nifU-like protein

0.41

0.01

Hp26695-0805

lipooligosaccharide 5G8 epitope biosynthesis-associated protein

0.42

0.02

Hp26695-1203a

Preprotein translocase subunit SecE

0.43

0.01

Hp26695-1219

hypothetical protein

0.43

0.04

Hp26695-0711

hypothetical protein

0.45

0.01

Hp26695-1180

pyrimidine nucleoside transport protein (nupC)

0.46

0.03

Hp26695-0502

hypothetical protein

0.46

0.03

Hp26695-1589

conserved hypothetical protein

0.47

0.01

Hp26695-0094

alpha-2-fucosyltransferase

0.49

0.02

Hp26695-1334

hypothetical protein

0.49

0.01

Hp26695-0415

conserved hypothetical integral membrane protein

0.49

0.01

Hp26695-0340

hypothetical protein

0.49

0.00

Hp26695-0798

molybdenum cofactor biosynthesis protein C (moaC)

0.49

0.03

Hp26695-0892

conserved hypothetical protein

0.50

0.03

Hp26695-0331

cell division inhibitor (minD)

0.59

0.04

Up-regulated genes:

Hp26695-0115

flagellin B (flaB)

1.91

0.03

Hp26695-0979

cell divison protein (ftsZ)

1.92

0.00

Hp26695-1469

outer membrane protein (omp31) (hopV)

1.96

0.00

Hp26695-1243

outer membrane protein (omp28) (babA)

1.96

0.00

Hp26695-0386

hypothetical protein

2.01

0.00

Hp26695-0831

conserved hypothetical ATP binding protein

2.04

0.01

Hp26695-0952

conserved hypothetical integral membrane protein

2.05

0.00

Hp26695-0311

hypothetical protein

2.16

0.00

Hp26695-0720

hypothetical protein

2.16

0.02

Hp26695-0943

D-amino acid dehydrogenase (dadA)

2.18

0.01

Hp26695-0896

outer membrane protein (omp19) (babB)

2.18

0.00

Hp26695-0590

ferredoxin oxidoreductase, beta subunit

2.23

0.01

Hp26695-0589

ferredoxin oxidoreductase, alpha subunit

2.27

0.01

Hp26695-1340

biopolymer transport protein (exbD)

2.30

0.00

Hp26695-1339

biopolymer transport protein (exbB)

2.36

0.00

Hp26695-0747

conserved hypothetical protein

2.44

0.03

Hp26695-0310

conserved hypothetical protein

2.48

0.00

Hp26695-1322

hypothetical protein

2.57

0.03

Hp26695-1076

hypothetical protein

2.59

0.00

Hp26695-1524

hypothetical protein

2.68

0.05

Hp26695-0721

hypothetical protein

2.99

0.00

Hp26695-0744

pseudogene

3.08

0.00

Hp26695-0719

hypothetical protein

3.34

0.01

Hp26695-0954

oxygen-insensitive NAD(P)H nitroreductase

3.53

0.00


The fold-change and the p-value are indicated. Bold fonts were used to highlight genes considered biologically relevant for the present study (surface-or motility-related genes). Full array datasets are in public databases as described in Methods.

Douillard et al. BMC Microbiology 2010 10:106   doi:10.1186/1471-2180-10-106

Open Data