The total number of mucosal lamina proprial CD25-positive T-cells. Cultured biopsy samples from treated celiac disease patients with and without mucosal IgA deposits and non-celiac control patients. Biopsies were cultured either with medium only or with PT-gliadin for 24 hours. The median values (horizontal line) and P values are calculated for each group showing a statistically significant increase in CD25+ cells only in those treated celiac disease cases who had small-bowel mucosal IgA deposits in the cultured biopsy samples.
Stenman et al. BMC Immunology 2008 9:6 doi:10.1186/1471-2172-9-6