|
Experimental timeline for raccoon vaccination (RCN-F1 and Raboral V-RG®) and blood sample collection |
|
| Day |
Activity |
|
|
|
| Pre-experiment |
Raccoon capture, quarantine, and pre-experiment blood sample (blood sample 1) |
| -2 |
Second pre-experiment blood samples (blood sample 2) |
| 0 |
108 pfu RCN-F1 administered to 10 raccoons at random |
| 30 |
Blood sample 3 |
| 33 |
107 pfu Raboral V-RG® administered to all raccoons |
| 69 |
Blood sample 4 |
| 97 |
Blood sample 5 |
| 118 |
108 pfu Raboral V-RG® administered to all raccoons |
| 149a |
Blood sample 6 |
| 179 |
Blood sample 7 |
| 210 |
Blood sample 8 |
| 237 |
Blood sample 9 |
| 252 |
Blood sample 10 |
|
aTo save resources, serologic assays were not conducted on samples collected from all sampling occasions. | |
Root et al. BMC Immunology 2008 9:57 doi:10.1186/1471-2172-9-57 |
|