Figure 5.

Summary schematic of the pathways regulating macropinocytosis. AMPK, AMP-activated protein kinase, ERK, extracellular-signal-regulated kinase, PI3K, phosphoinositide 3-kinase, PKC, protein kinase C, SOCS, suppressor of cytokine signaling, IRS-2, insulin receptor substrate 2, Jak, janus kinase.