BMC Immunology
Volume 9

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Research article

Divergence of canonical danger signals: The genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide

Hector R Wong¹ , Kelli Odoms¹ and Bhuvaneswari Sakthivel²

¹Department of Pediatrics, University of Cincinnati College of Medicine, Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center and Cincinnati Children's Research Foundation, Cincinnati, Ohio, USA

²Department of Pediatrics, University of Cincinnati College of Medicine, Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center and Cincinnati Children's Research Foundation, Cincinnati, Ohio, USA

author email corresponding author email

BMC Immunology 2008, 9:24doi:10.1186/1471-2172-9-24


Published:	30 May 2008

Additional files

Additional file 1:

3968 genes regulate in lps treated thp1 cells.xls, list of genes regulated in response to LPS alone.

Format: XLS Size: 745KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 2:

2921 genes regulate in heat shocked thp1 cells.xls, list of genes regulated in response to heat shock alone.

Format: XLS Size: 546KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 3:

merged uregulated lps network.xls, list of genes corresponding to two merged, upregulated networks in response to LPS alone and shown in Figure 3.

Format: XLS Size: 13KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 4:

network legend.pdf, legend for networks depicted in Figures 2, 3, and 5 to 8.

Format: PDF Size: 75KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 5:

merged upregulated heat shock network.xls, list of genes corresponding to two merged, upregulated networks in response to heat shock alone and shown in Figure 4.

Format: XLS Size: 14KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 6:

merged downregulated LPS network.xls, list of genes corresponding to two merged, downregulated networks in response to LPS alone and shown in Figure 5.

Format: XLS Size: 13KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 7:

merged downregulated heat shock network.xls, list of genes corresponding to two merged, downregulated networks in response to heat shock alone and shown in Figure 6.

Format: XLS Size: 13KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 8:

genes common to both lps and heat shock.xls, list of genes commonly regulated in THP1 cells treated with either LPS or heat shock.

Format: XLS Size: 130KB Download file

This file can be viewed with: Microsoft Excel Viewer