Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists

doi:10.1186/1471-2172-8-26

BMC Immunology

Volume 8

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Birmachu W
Gleason RM
Bulbulian BJ
Riter CL
Vasilakos JP
Lipson KE
Nikolsky Y

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Riter CL
Vasilakos JP
Lipson KE
Nikolsky Y
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Research article

Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists

Woubalem Birmachu¹ , Raymond M Gleason¹ , Barbara J Bulbulian¹ , Christie L Riter¹ , John P Vasilakos¹ , Kenneth E Lipson¹ and Yuri Nikolsky²

¹Pharmacology, 3M Pharmaceuticals, St Paul, Minnesota, USA

²GeneGo Inc, St. Joseph, Michigan, USA

author email corresponding author email

BMC Immunology 2007, 8:26doi:10.1186/1471-2172-8-26


Published:	12 October 2007

Additional files

Additional file 1:

Genes altered in expression 4 hr post-stimulation of pDC with 3M-852A and 3M-011. This file summarizes the log2 fold change in expression for 680 genes altered in expression upon treatment of pDC with 3M-852A and 3M-011, 4 hr post stimulation. Fold change in expression was calculated with respect to vehicle-treated samples from the same donor. Genes were selected if the probes sets had signal detection p-value less than 0.01 and an expression change p-value less than 0.005 across replicates for each TLR agonist.

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Additional file 2:

Legend describing symbols used in networks. Legend provides a key to the symbols used in the MetaCore networks.

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