Figure 4.

Comparison of the derived amino acid sequences of IGHV3-11 (A.) and IGHV3-11^cyno (B.) IgM genes encoding xenoantibodies in two porcine-cell infused animals, with reference to the human IGHV3-11 germline sequence from GenBank® (HSIGVH22B). * = residue is identical to one immediately above. Letters below the asterisks indicate amino acid substitutions.