Research article
Sexual dimorphism in immune response genes as a function of puberty
-
* Corresponding author: Kanneboyina Nagaraju knagaraju@cnmcresearch.org
1 Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
2 Research Center for Genetic Medicine, Children's National Medical Center, 111 Michigan Ave, NW, Washington DC, 20010, USA
3 National Institutes of Health, Bethesda, MD, USA
4 University of Pennsylvania, Philadelphia, PA, USA
BMC Immunology 2006, 7:2 doi:10.1186/1471-2172-7-2
Published: 22 February 2006Additional files
Additional File 1:
Genes up regulated during puberty in male and female mice.
Format: DOC Size: 26KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional File 2:
Genes down regulated during puberty in male and female mice.
Format: DOC Size: 38KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional File 3:
Genes differentially expressed in post-pubertal male and female mice.
Format: DOC Size: 40KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional File 4:
Effect of estrogen on FasL expression in activated CD8+ T cells. Purified CD8+ T cells were isolated and stimulated with plate-bound CD3/CD28 in the presence and absence of estrogen (10-8M) for 24 h. The cells were stained with PE-labeled anti-FasL antibodies. Filled area, isotype control; green line, CD3/CD28-stimulated cells; pink line, CD3/CD28 and estrogen.
Format: TIFF Size: 16KB Download file
Additional File 5:
IFN-γ levels in activated CD8+ T cells. Purified CD8+ T cells were cultured in the presence and absence of plate-bound Fas-Fc/CD3/CD28 in the presence and absence of estrogen. IFN-γ was estimated using a commercial ELISA kit.
Format: JPEG Size: 69KB Download file
