Figure 3.

Amino acid alignment of deer mouse (Pema), house mouse (Mus), rat (Rattus) and human (Homo) IL-12a. Sequences were aligned as described in Figure 1. The deer mouse fragment represents 28% of the polypeptide. The polypeptide includes helix A (underlined) and conserved cysteines noted with an asterisk (*). The conserved arginine (+) is involved with dimerization to the p40 subunit.