Table 2

Baseline immunological marker values of 81 PHID patients, ALTADIH Cohort 2007-2010
Unit Median IQR
Total circulating lymphocytes (TCL) cells/mm3 1384 (1017, 2000)
B cells CD19+ cells/mm3 128 (62, 193)
% TCL 9.37 (6.21, 12.91)
Naïve CD27-IgD+ % CD19+ 74.01 (56.42, 83.35)
Switched CD27-IgD- % CD19+ 2.62 (1.86, 5.16)
Marginal zone CD27 + IgD+ % CD19+ 9.42 (4.70, 15.37)
Switched memory CD27 + IgD- % CD19+ 8.07 (3.63, 19.45)
T cells CD3+ cells/mm3 1078 (746, 1585)
CD4+ cells/mm3 657 (422, 941)
CD8+ cells/mm3 329 (228, 524)
CD4+/CD8+ ratio 1.99 (1.30, 2.70)
CD8+ T cells
Naïve CD45RA + CCR7+ % CD8+ 18.01 (6.79, 36.07)
Central memory CD45RA-CCR7+ % CD8+ 1.25 (0.59, 2.48)
Effector memory CD45RA-CCR7- % CD8+ 34.39 (24.47, 46.90)
Terminal effector CD45RA + CCR7- % CD8+ 33.48 (23.31, 48.26)
Immunosenescent CD8 + CD57+ % CD8+ 15.97 (8.04, 31.75)
Activated T cells
HLA-DR CD3 + HLA-DR+ % CD3+ 12.87 (7.99, 20.37)
CD4 + HLA-DR+ % CD4+ 7.96 (5.14, 13.79)
CD8 + HLA-DR+ % CD8+ 24.49 (14.31, 41.11)
Regulatory T cells CD4 + CD25 + CD127- cells/mm3% TCL 32 1.10 (16, 63) (0.51, 1.76)
Natural Killer cells CD3-CD16 + CD56+ cells/mm3 126 (75, 194)
Dendritic cells
Myeloid mDC /ml 9381 (6597, 15611)
Plasmacytoid pDC /ml 4671 (2810, 7427)
Gammadelta cells cells/mm3 33 (15, 72)
Gammadelta 2 cells % GD 56.32 (22.19, 77.17)

IQR, interquartile range.

Picat et al.

Picat et al. BMC Immunology 2014 15:13   doi:10.1186/1471-2172-15-13

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