Table 1

Baseline characteristics of 81 PHID patients, ALTADIH Cohort, 2007-2010
Characteristics Distribution
Sociodemographic data
     Female, n (%) 48 (59)
     Median age at diagnosis in years (interquartile range) 41 (35–54)
     Median age at enrolment in years (interquartile range) 46 (38–58)
Clinical data, n (%)
Respiratory tract infections
     Otitis, sinusitis, nasopharyngitis, polyposis 64 (79)
     Bronchitis, pneumonia 65 (80)
     Bronchiectasis 21 (26)
Gastrointestinal tract infection
     Chronic diarrhea 16 (20)
     Acute diarrhea 13 (16)
     Lambliasis 11 (14)
PHID complications: at least one of the following 31 (38)
     Lymphoid hyperplasia 16 (20)
     Splenomegaly 14 (17)
     Autoimmune manifestations* 14 (17)
     Granulomatous disease 9 (11)
     Villous atrophy 5 (6)
     Chronic inflammatory intestinal disease 4 (5)
Therapeutic data, n (%)
Subcutaneous or intravenous immunoglobulin substitution 66 (81)

*Autoimmune anemia, autoimmune neutropenia, autoimmune thrombocytopenia, Hashimoto thyroiditis, Goujerot-Sjögren syndrome.

Location of biopsy proven granuloma: lymph node, digestive tract, spleen, bone narrow.

Picat et al.

Picat et al. BMC Immunology 2014 15:13   doi:10.1186/1471-2172-15-13

Open Data