Table 2

OVA or PepVacTB1specific antibody responses induced by intranasal administration.

Groups

IgG(OD) sera

IgA(OD) saliva

IgG1(OD) sera

IgG2a(OD) sera


I

AFCo1+Ova

0.80**

0.63**

1.5**

0.8274**

OVA

0.12

0.11

0.10

0.10


II

AFCo1+ PepVacTB1

1.10**

0.45*

1.63**

1.04**

PepVacTB1

0.2

0.1

0.056

0.105


Results of two independent experiments. Experiment I shows the results of co-administration of AFCo1 with OVA and Experiment II shows the results of co-administration of AFCo1 with PepVacTB1. Female BALB/c mice (n = 5) were inoculated i.n (3 doses with 7 days interval) with AFCo1 (50 µg) admixed with heterologous antigen OVA or PepVacTB1 (20 µg). Control groups were treated with OVA or PepVacTB1 (20 µg per dose per mouse) alone. The data are expressed as the OD means of samples measured at 492 nm. Significant differences between the means of different groups were determined. Asterisks denote significant differences between groups * p<0.05, ** p<0.01

Zayas et al. BMC Immunology 2013 14(Suppl 1):S4   doi:10.1186/1471-2172-14-S1-S4

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