Open Access Highly Accessed Research article

Serum biomarker analysis of collagen disease patients with acute-onset diffuse interstitial lung disease

Shomi Oka1, Hiroshi Furukawa1*, Kota Shimada23, Hiromi Hayakawa1, Naoshi Fukui1, Naoyuki Tsuchiya4 and Shigeto Tohma1

Author Affiliations

1 Clinical Research Center for Allergy and Rheumatology, Sagamihara Hospital, National Hospital Organization, 18-1 Sakuradai, Minami-ku, Sagamihara, Kanagawa, 252-0392, Japan

2 Department of Rheumatology, Sagamihara Hospital, National Hospital Organization, 18-1 Sakuradai, Minami-ku, Sagamihara, 252-0392, Japan

3 Tokyo Metropolitan Tama Medical Center, 2-8-29 Musashi-dai, Fuchu, 183-8524, Japan

4 Molecular and Genetic Epidemiology Laboratory, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan

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BMC Immunology 2013, 14:9  doi:10.1186/1471-2172-14-9

Published: 14 February 2013

Additional files

Additional file 1: Table S1:

Laboratory findings of collagen disease patients in the stable and the AoDILD state.

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Additional file 2: Table S2:

Cytokine expression ratios in sera of the patients between stable and AoDILD states.

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Additional file 3: Figure S1:

Biomarker levels in individual serum without pooling from collagen disease patients in the stable and AoDILD states.

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Additional file 4: Table S3:

Characteristics of collagen disease or RA patients with AoDILD.

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Additional file 5: Table S4:

Characteristics of collagen disease patients with AE-ILD or DI-ILD.

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Additional file 6: Table S5:

Characteristics of collagen disease patients with AoDILD with different clinical outcome.

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