Cat and grass allergen-induced CD154 expression in allergic and non-allergic individuals. Flow cytometric dot plots illustrate CD4+ CD154 expression in allergic and non-allergic individuals in (a, c, e, g) unstimulated T-cells and following PBMC stimulation with (b, d) cat dander and (f, h) grass pollen allergen extracts. Scatter dot plots demonstrate the background-corrected percentage of (c) cat allergen-specific and (d) grass allergen-specific CD154+ T cells in allergic and non-allergic individuals following allergen stimulation. PHA-induced CD154+ T cell population in non-allergic, (e) cat-allergic and (f) grass-allergic individuals.
Smith et al. BMC Immunology 2013 14:49 doi:10.1186/1471-2172-14-49