Table 3

Total and separate cell percentage and counts in peripherial blood and BAL fluid
Variable Lung cancer group Control group
Without COPD With COPD COPD Healthy individuals
Peripheral blood cells, mean ± SEM:
Leukocytes, x109l 8.57 ± 0.25*§ 8.71 ± 0.48*§ 5.81 ± 0.13* 5.35 ± 0.17
Neutrophils, % 65.34 ± 0.85*§ 67.45 ± 1.43*§ 61.77 ± 1.18* 56.92 ± 1.65
Neutrophils, x109l 5.72 ± 0.22*§ 5.96 ± 0.39*§ 4.35 ± 0.22* 3.70 ± 0.25
Lymphocytes, % 23.01 ± 0.79*§ 21.11 ± 1.21*§ 25.93 ± 0.99* 31.64 ± 1.45
Lymphocytes, x109l 1.88 ± 0.06 1.84 ± 0.10 1.78 ± 0.09 1.99 ± 0.09
Monocytes, % 8.60 ± 0.30*§ 8.10 ± 0.49*§ 6.82 ± 0.29 6.26 ± 0.42
Monocytes, x109l 0.87 ± 0.09*§ 0.88 ± 0.17*§ 0.46 ± 0.03 0.40 ± 0.03
Neutrophil/lymphocyte ratio, median (range) 2.92(0.93–13.42)*§ 3.08(1.18–8.84)* § 2.35(1.13–4.25)§ 1.86(1.16–3.21)
BAL fluid cells, mean ± SEM:
Neutrophils, % 8.01 ± 1.37*§ 7.94 ± 0.83*§ 14.10 ± 2.96* 1.29 ± 0.21
Neutrophils, x106/ml 0.39 ± 0.12*§ 0.41 ± 0.15*§ 0.54 ± 0.22* 0.08 ± 0.05
Macrophages, % 73.59 ± 1.51§ 72.89 ± 1.71§ 65.50 ± 3.19* 74.40 ± 1.77
Macrophages, x106/ml 3.24 ± 0.20§ 3.15 ± 0.30§ 2.95 ± 0.65* 3.21 ± 0.51
Lymphocytes, % 18.21 ± 1.02 18.81 ± 1.48 19.99 ± 1.80 21.97 ± 1.62
Lymphocytes, x106/ml 0.87 ± 0.34 1.03 ± 0.37 1.11 ± 0.53 0.63 ± 0.26
Eosinophils, % 0.29 ± 0.04 0.36 ± 0.06 0.41 ± 0.15 0.34 ± 0.11
Eosinophils, x106/ml 0.02 ± 0.01 0.01 ± 0.01 0.03 ± 0.01 0.02 ± 0.01

Data are expressed as mean ± SEM. *P < 0.05 when compared with healthy individuals; §P < 0.05 when compared to COPD group.

Vaguliene et al.

Vaguliene et al. BMC Immunology 2013 14:36   doi:10.1186/1471-2172-14-36

Open Data