A computational method to identify microRNA function and mRNA targets in T-cells. Target genes of significantly regulated microRNA between MS patients and controls, using TargetScan and Miranda algorithms, were compared with significantly differently expressed mRNA from peripheral blood T-cells between patients and controls. Squares indicate microRNA and circles mRNA. Red indicates increased expression and blue decreased expression between MS patients and controls.
Jernås et al. BMC Immunology 2013 14:32 doi:10.1186/1471-2172-14-32