Table 1

General characteristics of H1N1 vaccine recipients and controls
Unvaccinated (n = 12) Vaccinated (n = 81) Responders (n = 36) Non-responders (n = 44)
aCD4+ T cells/μL Mean ± SD 420 ± 235 529 ± 269 609 ± 277 475 ± 241
0–200 1 (8.3%) 9 (11%) 3 (8.3%) 5 (11%)
201–350 5 (42%) 13 (16%) 4 (11%) 9 (20%)
351–500 2 (17%) 15 (19%) 4 (11%) 11 (25%)
>500 4 (33%) 44 (54%) 25 (69%) 19 (43%)
Log10 viral load Median (IQR) 1.60 (1.60-2.09) 1.60 (1.60-2.70) 1.60 (1.60-2.34) 1.60 (1.60-3.07)
≤1.60 8 (67%) 50 (62%) 23 (64%) 27 (61%)
1.61-2.60 3 (25%) 11 (14%) 7 (19%) 4 (9.1%)
2.61-3.00 0 2 (2.5%) 1 (2.8%) 1 (2.3%)
3.01-4.00 0 6 (7.4%) 1 (2.8%) 5 (11%)
>4.00 1 (8.3%) 12 (14%) 4 (11%) 7 (16%)
Age (years) Mean ± SD 45.7 ± 6.6 45.2 ± 7.2 44.2 ± 7.5 46.2 ± 7.0
Male 8 (67%) 56 (69%) 27 (75%) 29 (66%)
Female 4 (33%) 25 (31%) 9 (25%) 16 (36%)
bPre-existing anti-H1N1 ND 28 (35%) 22 (61%) 6 (14%)

aNumber of CD4+ T cells/μL peripheral blood at time nearest to, but before H1N1 vaccination.

bNumber of individuals in each group with antibodies against H1N1 HA before vaccination.

Kelly et al.

Kelly et al. BMC Immunology 2012 13:49   doi:10.1186/1471-2172-13-49

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