Table 4

Stimulus-dependent regulation of RAGE and ICAM-1-mediated firm leukocyte adhesion in inflamed postcapillary venules of the cremaster muscle

Trauma-induced inflammation

TNF-α-induced inflammation

Stimulation:

None

fMLP

KC

None

fMLP

ICAM-1 - LFA-1

+^b

+^{a, c}

+^a

-^b

-^{a, c}

RAGE - Mac-1

+^b

-^a

-^a

+^b

+^a

Additional yet unknown integrin ligands

-^b

-^a

-^a

+^b

-^a

^a this study, ^b reference [3], ^c in part reference [10]

Frommhold et al. BMC Immunology 2011 12:56   doi:10.1186/1471-2172-12-56