IgE and IgG passive anaphylaxis in 129S5 and BALB/c mice. a) Rectal temperature 0-60 minutes and (b) maximal temperature change at 30 minutes and (c) Plasma histamine concentration at 5 minutes in control Ig and anti-IgE-treated (10 μg/200 μl saline) 129S5- and BALB/c mice. d) Rectal temperature 0-60 minutes and (e) maximal temperature change at 30 minutes in control Ig and anti-FcγRII/III-treated (500 μg/200 μl saline) 129S5 and BALB/c mice. (n = 6) Data represent mean ± SEM. Data were analyzed by one-way analysis of variance (ANOVA) and a post-hoc comparison test (Tukey-Kramer). (a) Triple asterisks indicate a P value < 0.001 compared with BALB/c + Anti-IgE. (b, c and e) Single asterisk indicates a P value < 0.05. n.s. not significant.
Arumugam et al. BMC Immunology 2011 12:14 doi:10.1186/1471-2172-12-14