Additional file 1.

Clinical Score and Body Mass of CAIA Mice Treated with Dexamethasone. Female DBA/1 mice injected with arthritogenic antibodies and LPS develop RA and begin treatment by day 6. (A) Total clinical score of mice treated with vehicle or dexamethasone, three times a week. Clinical score definitions can be found in the materials and methods. N = 10 per group, *p < 0.001, Mann-Whitney, two-tailed test. (B) Mean body mass of all mice treated, no significant difference observed between any group, N = 10 mice per group. All graphs show Mean ± SEM. (C) Paw IL-2 and (D) TNFα concentration sampled in 3 mg of total protein prepared as described in the materials and methods *p < 0.05.

Format: PDF Size: 53KB Download file

This file can be viewed with: Adobe Acrobat Reader

Lu et al. BMC Immunology 2010 11:55   doi:10.1186/1471-2172-11-55