BMC Immunology

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Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated with CTLA4 and TGFβ gene variants

Marta Barreto, Ricardo C Ferreira, Lara Lourenço, Maria F Moraes-Fontes, Eugénia Santos, Miguel Alves, Cláudia Carvalho, Berta Martins, Rita Andreia, João F Viana, Carlos Vasconcelos, Luísa Mota-Vieira, Carlos Ferreira, Jocelyne Demengeot and Astrid M Vicente*

BMC Immunology 2009, 10:5 doi:10.1186/1471-2172-10-5

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Defective response of CD4+ T cells to retinoic acid and TGFβ in systemic lupus erythematosus

Eric S Sobel, Todd M Brusko, Ed J Butfiloski, Wei Hou, Shiwu Li, Carla M Cuda, Ariana N Abid, Westley H Reeves, Laurence Morel Arthritis Research & Therapy 2011, 13:R106 (27 June 2011)

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Parasite immunomodulation and polymorphisms of the immune system

Rick M Maizels Journal of Biology 2009, 8:62 (5 August 2009)

Rick Maizels discusses a recent paper in BMC Biology on wild mammals that lend support to the hygiene hypothesis, and explains why genetic variants that reduce parasite-induced immunosuppression are associated with an increase in allergic reactions.