BMC Immunology

official impact factor 3.00

Open Access Highly Access Research article

The effect of caffeic acid phenethyl ester on the functions of human monocyte-derived dendritic cells

Li-Chieh Wang1, Yu-Li Lin2, Yu-Chih Liang3, Yao-Hsu Yang1, Jyh-Hong Lee1, Hsin-Hui Yu1, Wen-Mein Wu4 and Bor-Luen Chiang1*

Author Affiliations

1 Department of Pediatrics, National Taiwan University Hospital, 7 Chung-Shan South Rd, Taipei 100, Taiwan, Republic of China

2 Department of Medical Research, National Taiwan University Hospital, 7 Chung-Shan South Rd, Taipei 100, Taiwan, Republic of China

3 School of Medical Laboratory Science & Biotechnology, College of Medicine, Taipei Medical University, 250 Wu-Xin Street, Taipei 110, Taiwan, Republic of China

4 Department of Nutritional Science, Fu-Jen Catholic University, 510 Chung-Cheng Rd, Hsinchuang, Taipei County 24205, Taiwan, Republic of China

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BMC Immunology 2009, 10:39 doi:10.1186/1471-2172-10-39

Published: 16 July 2009

Additional files

Additional file 1:

Figure S1 – LPS induced IκBα phosphorylation and degradation in time kinetics. Human MoDCs from healthy subjects were pretreated with CAPE (10 μM) for 2 hours, then stimulated by LPS (100 ng/mL) in the indicated time. Cell lysate were collected and the levels of (A) phosphorylated IκBα and (B) IκBα were assayed by Western blotting with indicated Abs. Anti-α-tubulin mAb was for internal control.

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