Table 2

Gene Ontology terms which are over- or under-represented among the rapidly or slowly evolving cichlid ORFs. Hypergeometic p-values are reported uncorrected for multiple testing. The number of ORFs of deviating evolutionary rate (#) relative to the number of core set ORFs (total) is given.

Representation

GO-ID

p-value

#

total

Description


biological process

42 with higher p-distance (647 annotated)

over

none

under

GO:0050896

0.0161

1

86

response to stimulus

GO:0009987

0.0439

12

273

cellular process

molecular function

44 with higher p-distance (675 annotated)

none

Cellular component

40 with higher p-distance (619 annotated)

over

GO:0015629

0.0327

6

39

actin cytoskeleton

under

none

biological process

103 with lower p-distance (647 annotated)

over

GO:0009987

0.0024

57

273

cellular process

over

GO:0007243

0.0052

8

19

protein kinase cascade

over

GO:0007155

0.0205

7

19

cell adhesion

over

GO:0040007

0.0208

6

15

growth

over

GO:0007154

0.0230

25

109

cell communication

over

GO:0007267

0.0071

7

16

cell-cell signaling

over

GO:0016477

0.0290

5

12

cell migration

over

GO:0040008

0.0290

5

12

regulation of growth

over

GO:0007409

0.0308

3

5

axonogenesis

over

GO:0007610

0.0308

3

5

behavior

over

GO:0015674

0.0308

3

5

di-, tri-valent inorganic cation transport

over

GO:0019752

0.0376

10

35

carboxylic acid metabolic process

over

GO:0007067

0.0402

4

9

mitosis

over

GO:0007417

0.0402

4

9

central nervous system development

under

GO:0008152

0.0016

63

477

metabolic process

under

GO:0046907

0.0180

2

44

intracellular transport

under

GO:0045045

0.0295

0

20

secretory pathway

under

GO:0009117

0.0421

0

18

nucleotide metabolic process

molecular function

110 with lower p-distance (675 annotated)

over

GO:0004930

0.0157

4

7

G-protein

over

GO:0003774

0.0233

6

15

motor activity

over

GO:0005262

0.0264

2

2

calcium channel

over

GO:0008047

0.0324

6

16

enzyme activator activity

over

GO:0005509

0.0333

12

43

calcium ion binding

over

GO:0019899

0.0435

4

9

enzyme binding

under

GO:0005525

0.0116

1

36

GTP binding

under

GO:0005198

0.0407

8

85

structural molecule activity

under

GO:0051082

0.0467

0

17

unfolded protein binding

under

GO:0003743

0.0467

0

17

translation initiation factor activity

under

GO:0003924

0.0481

1

27

GTPase activity

under

GO:0003676

0.0483

17

147

nucleic acid binding

cellular component

97 with lower p-distance (619 annotated)

over

GO:0016021

0.0096

22

88

integral to membrane

over

GO:0015630

0.0388

5

13

microtubule cytoskeleton

over

GO:0005625

0.0479

6

18

soluble fraction

over

GO:0005615

0.0479

6

18

extracellular space

under

GO:0032991

0.0001

19

222

macromolecular complex

under

GO:0043234

0.0015

18

195

protein complex

under

GO:0043226

0.0089

56

425

organelle

under

GO:0030529

0.0139

4

65

ribonucleoprotein complex

under

GO:0005829

0.0267

3

51

cytosol

under

GO:0005739

0.0311

6

75

mitochondrion


Salzburger et al. BMC Genomics 2008 9:96   doi:10.1186/1471-2164-9-96

Open Data