Differential replication dynamics for large and small Vibrio chromosomes affect gene dosage, expression and location

doi:10.1186/1471-2164-9-559

BMC Genomics
Volume 9

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Research article

Differential replication dynamics for large and small Vibrio chromosomes affect gene dosage, expression and location

Rikard Dryselius¹^,2 , Kaori Izutsu¹ , Takeshi Honda² and Tetsuya Iida¹

¹Laboratory of Genomic Research on Pathogenic Bacteria, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan

²Department of Bacterial Infections, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan

author email corresponding author email

BMC Genomics 2008, 9:559doi:10.1186/1471-2164-9-559


Published:	26 November 2008

Additional files

Additional file 1:

RT-qPCR primers with target positions. The table shows sequences and target positions for RT-qPCR primers.

Format: PDF Size: 103KB Download file

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Additional file 2:

Comparison of gDNA from non-replicating cell samples against gDNA from exponentially growing cells. The figure shows relative amounts of origin and terminus proximate DNA in differently produced non-replicating samples of V. parahaemolyticus, V. cholerae, and V. vulnificus in comparison to exponentially growing cell samples.

Format: PDF Size: 138KB Download file

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Additional file 3:

Periodic expression patterns from the large and small chromosome of V. parahaemolyticus. The figure indicates periodicities in expression levels along both chromosomes of V. parahaemolyticus.

Format: PDF Size: 455KB Download file

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Additional file 4:

Distribution of COG classified genes within three different parts of five Vibrionaceae genomes. The table shows COG sizes within the early and late replicated parts of the large chromosome and the small chromosome in five Vibrionaceae species.

Format: PDF Size: 137KB Download file

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Additional file 5:

COG classification of all, essential and highly growth contributing E. coli genes. The table shows the distribution of all, growth essential and highly growth contributing E. coli genes within each of 21 COG categories.

Format: PDF Size: 115KB Download file

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