Migration rate signature derived from SAM analysis of union of migratory and stationary signatures; fast migrating cell lines colored in green, slow migrating cell lines colored in red (A). K-means (k = 3) identified three populations in malignant astrocytoma samples stratified by age that were visualized by multidimensional scaling (MDS); young (< median age) (B) and old patients (> median age) (C). Kaplan-Meier survival analysis for clusters derived from k-means stratified by age; young (D), old (E) show significant differences in overall survival.
Demuth et al. BMC Genomics 2008 9:54 doi:10.1186/1471-2164-9-54