Open Access Highly Accessed Research article

Comparative genomics of wild type yeast strains unveils important genome diversity

Laura Carreto12, Maria F Eiriz1, Ana C Gomes2, Patrícia M Pereira1, Dorit Schuller3 and Manuel AS Santos1*

  • * Corresponding author: Manuel AS Santos msantos@ua.pt

  • † Equal contributors

Author Affiliations

1 Departamento de Biologia & CESAM, Universidade de Aveiro, 3810-193 Aveiro, Portugal

2 BIOCANT, Centro de Inovação em Biotecnologia, Parque Tecnológico de Cantanhede, Núcleo 04, Lote 3, 3060-197 Cantanhede, Portugal

3 Centro de Biologia Molecular e Ambiental (CBMA) Universidade do Minho, Braga, Portugal

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BMC Genomics 2008, 9:524  doi:10.1186/1471-2164-9-524

Published: 4 November 2008

Additional files

Additional File 1:

Hybrid detection by PCR-RFLP analysis. PCR-RFLP of five distinct loci located in different chromosomes.

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Additional File 2:

CGH Miner karyoscope maps. Karyoscope maps of the 16 wild-type strains analyzed (S2A-S2P) and the baseline karyoscope obtained for strain S288C (S2Q).

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Additional File 3:

Genome alterations between YJM789 and S288C and this study. Genome alterations found in the consensus plot obtained for the wine strains are compared of the clinical strain YJM789 whose genome is fully sequenced.

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Additional File 4:

Confirmation of microarray probe targets for a selected group of ORF. Specificity and homology of a set of microarray probes using BLAST alignment against the genomes of S. cerevisiae strains S288C, RM11-1a and YJM789.

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