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Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals

Ruben van Boxtel, Pim W Toonen, Mark Verheul, Henk S van Roekel, Isaac J Nijman, Victor Guryev and Edwin Cuppen*

BMC Genomics 2008, 9:460  doi:10.1186/1471-2164-9-460