Table 10

Top ten gender-dependent cancer-related genes that have the greatest fold change due to hepatocyte RXRα deficiency.

Male vs. Female (6 month old mice)


Genes in C

Folds (WT)

Folds (KO)

Fold change due to RXRα deficiency


MYC

33.49

5.52

6.07

CDKN1A

27.04

5.03

5.38

CYP17A1

-32.26

-10.32

3.13

BTG2

10.53

3.48

3.03

HSPA1B

23.96

8.35

2.87


ABCB1

-8.77

-19.23

0.46

B4GALNT1

-2.73

-6.06

0.45

PTP4A3

-4.33

-10.67

0.41

CXCL2

2.89

8.40

0.34

HSPB1

6.40

19.48

0.33


Guo et al. BMC Genomics 2008 9:403   doi:10.1186/1471-2164-9-403

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