Table 4 |
||||||
|
Microarray Experiment Patient Clinical Details |
||||||
|
Patients |
Sex |
Age |
Duodenal histology |
Other histology, clinical information |
Antibody status |
Microarray number |
|
|
||||||
|
Coeliac |
||||||
|
1 |
Female |
61 |
Grade 3a |
none |
tTG + |
1 |
|
2 |
Female |
45 |
Grade 3b |
Barrett's oesophagus |
tTG + |
2 |
|
3 |
Female |
22 |
Grade 1 |
none |
tTG + |
3 |
|
4 |
Female |
31 |
Grade 3c |
none |
tTG + |
4 |
|
5 |
Female |
36 |
Grade 3c |
mild reflux oesophagitis |
tTG + |
5 |
|
|
||||||
|
Control |
||||||
|
6 |
Female |
58 |
NDM |
mild reflux oesophagitis |
nk |
1 |
|
7 |
Female |
51 |
NDM |
moderate reflux oesophagitis |
tTG - |
2 |
|
8 |
Female |
25 |
NDM |
none |
nk |
3 |
|
9 |
Female |
30 |
NDM |
superficial acute and chronic gastric inflammation |
nk |
4 |
|
10 |
Female |
26 |
NDM |
mild reflux oesophagitis |
tTG - |
5 |
|
|
||||||
|
Histology grade: 0 = normal; 1 = raised intraepithelial lymphocytes (IELs); 2 = increase in IELs with crypt hyperplasia; 3a = increase in IELs, crypt hyperplasia, mild villous atrophy; 3b = increase in IELs, crypt hyperplasia, marked villous atrophy; 3c = total villous atrophy [37]. NDM = normal duodenal mucosa. tTG, tissue transglutaminase antibody. nk, not known. |
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|
Bracken et al. BMC Genomics 2008 9:377 doi:10.1186/1471-2164-9-377 |
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