Table 8

Analysis of A/T heteropolymeric sequence occurrences

A/T Heteropolymeric Sequences

5-mers

6-mers


Direct

Indirect

Direct

Indirect


AT, TA

observed

0.500

0.294

0.533

0.214

yeast

0.180

0.180

0.180

0.180

p-value

< .0001

0.007

< .0001

0.228

ATA, TAT

observed

0.359

0.157

0.396

0.125

yeast

0.065

0.065

0.065

0.065

p-value

< .0001

0.004

< .0001

0.033

ATAT, TATA

observed

0.192

0.029

0.222

0.071

yeast

0.024

0.024

0.024

0.024

p-value

< .0001

0.418

< .0001

0.022

ATATA, TATAT

observed

0.154

0.000

0.167

0.036

yeast

0.010

0.010

0.010

0.010

p-value

< .0001

0.662

< .0001

0.090

ATATAT, TATATA

observed

-

-

0.083

0.000

yeast

-

-

0.010

0.010

p-value

-

-

< .0001

0.579


The rate of occurrence (observed) of 2–6 nt A/T heteropolymeric sequences in the unique 5-mer and 6-mer sequences listed in Tables 4-7 for the direct and indirect gene categories was compared to the rate of occurrence (yeast) in the 200 nt upstream region of 5869 yeast genes using a 1-sided Z-test. Highly significant p-values are shown in bold.

Eckdahl et al. BMC Genomics 2008 9:32   doi:10.1186/1471-2164-9-32

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